Sökning: "chronic hepatitis C"

Visar resultat 1 - 5 av 65 avhandlingar innehållade orden chronic hepatitis C.

  1. 1. Hepatitis C virus infection : a nationwide study of associated morbidity and mortality

    Författare :Ann-Sofi Duberg; Erik Bäck; Karl Ekdahl; Rolf Hultcrantz; Anders Blaxhult; Johan Carlson; Örebro universitet; []
    Nyckelord :HCV; hepatitis C; epidemiology; non-Hodgkin s lymphoma; NHL; multiple myeloma; primary liver cancer; HCC; mortality; inpatient care; hospitalization; MEDICINE; MEDICIN; Infektionssjukdomar; Infectious Diseases; Epidemiology; Epidemiologi; Medicin; Medicine;

    Sammanfattning : The hepatitis C virus (HCV) was characterised in 1989. HCV was transmitted through transfusion of blood/blood products, but injection drug use is now the most common route of transmission. LÄS MER

  3. 2. Towards the elimination of hepatitis C : identifying the infected population, and remaining hepatitis C related risks after successful treatment

    Författare :Charlotte Lybeck; Ann-Sofi Duberg; Soo Aleman; Scott Montgomery; Magnus Gottfredsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HCV; HCC; epidemiology; MTCT; pregnancy; DAA; OCI;

    Sammanfattning : Chronic Hepatitis C virus (HCV) infection can lead to liver fibrosis and cirrhosis with increased risk of hepatocellular carcinoma (HCC) and liver failure. The World Health Organisation (WHO) has set a goal to eliminate viral hepatitis as a global health threat by 2030. LÄS MER

  4. 3. GB virus C/hepatitis G virus infection: clinical, histological and epidemiological aspects

    Författare :Per Björkman; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endoscopy; nosocomial; sexual transmission; parenteral transmission; blood donor; ALT; liver disease; hepatitis; GBV-C HGV; HCV; Infections; Infektioner;

    Sammanfattning : GBV-C/HGV is a blood-borne virus related to the hepatitis C virus. We studied GBV-C/HGV infection in different populations, its transmission, and its association with liver disease. GBV-C/HGV viraemia was detected by PCR in 19/576 blood donors. Donors with normal and elevated ALT levels had similar rates of viraemia (1. LÄS MER

  5. 4. Chronic hepatitis C infection. With special reference to prevalence, aggravating factors and longterm outcome

    Författare :Hans Verbaan; Gastroenterologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastro-enterology; alpha1-antichymotrrypsin; kollagen markers; hepatocellular cancer; cirrhosis; Hepatitis C infection; alcohol; Gastroenterologi;

    Sammanfattning : Since the discovery of hepatitis C virus (HCV) in 1989, it has proved to be a formidable health problem with a major impact on morbidity and mortality throughout the world. In this investigation, patients with chronic hepatitis C infection have been studied with special reference to prevalence, aggravating factors and longterm outcome. LÄS MER

  7. 5. Design and Synthesis of Hepatitis C Virus NS3 Protease Inhibitors : Targeting Different Genotypes and Drug-Resistant Variants

    Författare :Anna Karin Belfrage; Anja Sandström; Ulf Ellervik; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hepatitis C virus; HCV; NS3 protease inhibitors; structure-activity relationship; 2 1H -pyrazinone; quinazoline; resistance; Pd catalysis; Medicinal Chemistry; Läkemedelskemi; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Since the first approved hepatitis C virus (HCV) NS3 protease inhibitors in 2011, numerous direct acting antivirals (DAAs) have reached late stages of clinical trials. Today, several combination therapies, based on different DAAs, with or without the need of pegylated interferon-α injection, are available for chronic HCV infections. LÄS MER