Sökning: "childhood acute lymphoblastic leukaemia"

Visar resultat 16 - 18 av 18 avhandlingar innehållade orden childhood acute lymphoblastic leukaemia.

1. 16. Responses to Tumour initiating factors and Regulation of Normal and Malignant Haematopoiesis

   Författare :Eva Diffner; Malmö Patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The haematopoietic stem cell (HSC) resides within a specific environment enabling it to retain its self-renewal capacity or quiescent state. It is proposed that the HSC niche is hypoxic, a milieu within which the HSC is protected from intrinsic and extrinsic stimuli. LÄS MER

3. 17. Regulation of antibody production in immunocompromised patients

   Författare :Anna Nilsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Hypergammaglobulinemia; specific antibodies; memory B- cells; microenvironment;

   Sammanfattning : The aim of this thesis was to study B-cell function and the regulation of specific antibody (Abs) production in immunocompromised individuals. As models, we have studied children with acute lymphoblastic leukaemia (ALL) and patients with IRV-I infection. LÄS MER

4. 18. Pharmacogenetic studies of thiopurines : focus on thiopurine methyltransferase

   Författare :Malin Lindqvist Appell; Michel Eichelbaum; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Pharmacogenetics represents the study ofvariability in drug response due to genetic variations. The thiopurines (6-mercaptopurine, 6-thioguanine and azathioprine) are prodrugs which require metabolic transformation to exert effect. LÄS MER