Sökning: "cell mediated immunity"
Visar resultat 1 - 5 av 193 avhandlingar innehållade orden cell mediated immunity.
1. Restoring antitumor immunity with dendritic cell reprogramming strategies. Reprogramming cancer cells to antigen-presenting cells
Sammanfattning : For the past two decades, immunotherapy revolutionized cancer treatment. However, responses vary significantly among eligible patients and some cancer types are not yet open to immunotherapy. Several mechanisms contribute to immunotherapy resistance, including loss of antigen presentation machinery and immunosuppression. LÄS MER
2. Cell-mediated immunity to flavivirus infections
Sammanfattning : NK cells and T cells constitute a major part of the cell-mediated immune system and play important roles in the host defense against viral infections. Most current knowledge of cell-mediated immune responses to primary acute viral infections comes from murine models, while relatively less is known about human responses to, in particular, acute viral infections. LÄS MER
3. Stress and immune signaling in a Drosophila tumor model
Sammanfattning : Cancer cells contain multiple biological alterations that allow them to escape from host surveillance mechanisms. One of the mechanisms that play an essential role in host protection against tumor growth is immunity. LÄS MER
4. Enhancing T cell mediated immunity in DNA vaccination
Sammanfattning : For centuries infectious diseases have been one of the main causes of death in the world. With the invention of vaccine technology 200 years ago, we have been able to impede and even eradicate several dangerous pathogens. LÄS MER
5. Phagocyte-induced apoptosis in natural killer cells and T cells. Role of reactive oxygen species and regulation by histamine
Sammanfattning : Malignant tumors frequently contain an infiltrate of leukocytes, usually cells of the monocyte/macrophage lineage and lymphocytes with anti-tumor activity such as natural killer (NK) cells and T cells. Clinical and experimental data suggest that monocytes/macrophages in tumors inhibit functions of adjacent NK cells/T cells and thereby suppress lymphocyte-dependent anti-tumor immunity. LÄS MER