Sökning: "cell attachment"
Visar resultat 1 - 5 av 207 avhandlingar innehållade orden cell attachment.
1. Adhesion Dependent Signals : Cell Survival, Receptor Crosstalk and Mechanostimulation
Sammanfattning : The integrin family of cell surface receptors is evolutionary conserved and found in all multicellular animals. In humans 8-alpha and 18-beta integrins are non-covalently associated into 24 dimers. Integrins mediate cell-extracellular matrix and cell-cell interactions and participate in cell signalling. LÄS MER
2. Regulation of docking and priming in pancreatic α- and β-cells
Sammanfattning : The secretion of islet hormones from endocrine cells of the pancreas plays vital roles in maintaining glucose homeostasis. Dysfunction of these cells leads to diabetes, a devastating metabolic disorder affecting millions worldwide, but underlying mechanisms remain poorly understood. LÄS MER
3. From Tissue Engineering to Engineering Education Research: Designing in vitro cell microenvironments and undergraduate research experiences
Sammanfattning : This thesis looks at tissue engineering from two perspectives that are closely interconnected with each other: 1) Research in the discipline of tissue engineering that aims to advance our knowledge in the field, and 2) research on how students learn tissue engineering through undergraduate research.In the body, cells are constantly exposed to a concert of different signaling factors that steer their behavior. LÄS MER
4. Studies on various culture systems for chondrocytes and osteoblasts
Sammanfattning : Osteoarthritis and osteochondral defects are ailments that are increasing in frequency as the lifespan of the population increases and sedentary lifestyle becomes more common. Osteoarthritis is an inflammatory disease that causes the progressive degeneration of articular surfaces and the underlying bone. LÄS MER
5. Integrin Signaling in Cell Adhesion and Mechanotransduction : Regulation of PI3K, AKT, and ROS
Sammanfattning : Integrins are a family of conserved cell surface receptors found throughout the animal kingdom. They comprise 24 dimers in mammals, and regulate a number of processes including cell survival, differentiation, and migration. LÄS MER