Sökning: "celiac type 1 diabetes"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden celiac type 1 diabetes.

1. 1. The Perfect Storm? Gluten and type 1 diabetes

   Författare :Emma Adlercreutz; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NKG2D; Celiac disease autoimmunity; Gluten; Type 1 diabetes; Perinatal risk;

   Sammanfattning : Aim: The general objective of the present research was to study the association between type 1 diabetes and celiac disease, and the effects of dietary gluten on the risk of developing type 1 diabetes. More specific aims were as follows: to estimate the prevalence of celiac-disease-associated autoantibodies in children with type 1 diabetes; to study the connection between non-HLA genetic risk markers and autoantibodies associated with type 1 diabetes and celiac disease during the first year after diagnosis of type 1 diabetes; to investigate the effect of gluten on the risk of developing type 1 diabetes; to evaluate the impact of perinatal factors on the risk of developing both type 1 diabetes and celiac disease. LÄS MER

3. 2. Immunogenetics of Type 1 diabetes and Celiac disease

   Författare :Shehab Abdulaziz Alshiekh; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; celiac disease; type 1 diabetes; children; genetics; human leukocyte antigen; next generation sequencing;

   Sammanfattning : AbstractThe primary purpose of understanding disease etiology is to explain how a specific phenotype is determined by genotype. In pursue of this aim, exploring the diversity in DNA sequence variants that affect biomedical traits, especially those related to the onset and progression of genetically determined human disease. LÄS MER

4. 3. Triggers of autoimmunity. Studies on gestational events

   Författare :Sabina Lindehammer; Celiaki och diabetes; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet autoantibodies; pregnancy; type 1 diabetes; celiac disease;

   Sammanfattning : Objective The primary aim of this thesis was to test whether gestational exposure to environmental factors may induce islet autoimmunity. The second aim was to determine to what extent the exposure to viruses or other environmental factors is a risk factor for type 1 diabetes in the offspring. LÄS MER

5. 4. Pinpointing biomarkers of importance for children with combined type 1 diabetes and celiac disease

   Författare :Andrea Tompa; Maria Faresjö; Karin Åkesson; Mikael Karlsson; Jönköping University; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; celiac disease; children; biomarkers; immune markers; flow cytometry; cryopreservation; T cells; T-regulatory cells; B cells; B-regulatory cells; cytokines; chemokines; acute phase proteins; adipocytokines; matrix metalloproteinases;

   Sammanfattning : Type 1 diabetes (T1D) and celiac disease are both characterized by an autoimmune feature. The diseases also share the same risk genes, and thereby patients have an increased risk of developing the other disease subsequently. LÄS MER

7. 5. Combinations of type 1 diabetes, celiac disease and allergy : An immunological challenge

   Författare :Anna Kivling; Maria Faresjö; Lennart Nilsson; Karin Åkesson; Ragnar Bjarnason; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : The immune system is composed of a complex network of different cell types protecting the body against various possible threats. Among these cells are T-helper (Th) cells type 1 (Th1) and type 2 (Th2), as well as T regulatory (Treg) cells. LÄS MER