Sökning: "cDNA microarray"

Visar resultat 1 - 5 av 56 avhandlingar innehållade orden cDNA microarray.

1. 1. Genetic Profiling in Soft Tissue Sarcoma

   Författare :Princy Francis; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; synovial sarcoma; prognosis; Cytology; SS18-SSX; intratumor heterogeneity; aCGH; array comparative genomic hybridization; gene expression analysis; microarray; cDNA; Soft tissue sarcoma; cancerology; Cytologi; onkologi; cancer;

   Sammanfattning : Soft tissue sarcomas (STS) are a heterogeneous group of highly malignant mesenchymal tumors that account for ~1% of all malignancies. Frequent heterogeneity and pleomorphism along with suboptimal diagnostic reproducibility and insufficient prognostic markers make clinical management of these tumors difficult. LÄS MER

3. 2. Gene Expression Profiling of Hereditary Breast Cancer

   Författare :Ingrid Hedenfalk; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; non-BRCA1 BRCA2; BRCAx; MYB; cDNA microarray; gene expression profiling; tissue microarray; Cytology; oncology; cancerology; Cytologi; cancer; onkologi; BRCA2; Hereditary breast cancer; BRCA1;

   Sammanfattning : [abstract missing].... LÄS MER

4. 3. Development and Application of Human Chromosome 22 Genomic Microarray : Chromosome 22-Associated Disorders Analyzed by Array-Based Comparative Genomic Hybridization

   Författare :Magdalena Benetkiewicz; Jan Dumanski; Niklas Dahl; Frank Speleman; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; DNA copy number changes; chromosome 22; genomic microarray; array-CGH; schwannoma; neurofibromatosis type 2; ovarian carcinoma; breast cancer; Wilms tumor; Genetik; Genetics; Genetik;

   Sammanfattning : The array-based form of comparative genomic hybridization (array-CGH) is a new methodology that has shown to be of significant importance. This thesis focuses on the development of array-CGH with the aim to define candidate regions/genes on chromosome 22 in a wide spectrum of cancer-related conditions. LÄS MER

5. 4. Transcript profiling of small tissue samples using microarray technology

   Författare :Maria Sievertzon; Joakim Lundeberg; Tom Freeman; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Gene expression analysis; transcriptomics; microarray analysis; 3’-tag signature amplification; neural stem cells; Biologi; Biology; Biologi;

   Sammanfattning : Through a number of biological, technological and computational achievements during the 20th century and the devoted work of hundreds of researchers the sequence of the human and other genomes are now available in public databases. The current challenge is to begin to understand the information encoded by the DNA sequence, to elucidate the functions of the proteins and RNA molecules encoded by the genes as well as how they are regulated. LÄS MER

7. 5. Transcriptome Analyses of the Nematode-trapping Fungus Monacrosporium haptotylum

   Författare :Margareta Tholander; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Biologi; Microbiology; bacteriology; virology; mycology; Pathogenic fungi; Nematophagous fungi; Nematodes; Biological control; cDNA microarray; Transcriptome analysis; Nematode-trapping fungi; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Nematode-trapping fungi are soil living organisms with the ability to infect and kill nematodes. These fungi have developed specialized infection structures, traps for the capture of nematodes. To be able to identify genes in nematode-trapping fungi that are involved in the infection of nematodes cDNA microarrays were constructed. LÄS MER