Sökning: "c-kit"
Visar resultat 21 - 25 av 41 avhandlingar innehållade ordet c-kit.
21. Dissecting the roles of viral T-antigens in Merkel cell carcinoma
Sammanfattning : Merkel cell carcinoma (MCC) is a rare but aggressive form of skin malignancy with increasing incidence. Merkel cell polyomavirus (MCPyV) is associated with ~80% of MCCs, and a minority is caused by ultra-violet (UV)-induced DNA damage. The MCPyV T-antigens are major drivers for MCC oncogenesis. LÄS MER
22. Protein tyrosine kinases in insulin producing cells : Expression and putative importance for beta-cell function
Sammanfattning : Protein tyrosine kinases are of importance for cell replication and differentiation in manysystems. The mechanisms controlling the replication and differentiation of insulin producingcells are unknown. LÄS MER
23. Transcriptional Regulation by Hypoxia-Inducible Factors in Tumor Cells
Sammanfattning : Cancer is a major cause of human morbidity and mortality, and the risk of developing cancer is about one in three life times. Neuroblastoma is the most common extra-cranial solid tumor among children and arises from early sympathetic nervous system (SNS) cells arrested in their development. LÄS MER
24. Embryonic and adult cardiac stem cells : molecular, electrophysical and immunological characteristics for cardiac repair
Sammanfattning : Background: The concept of myocardial regeneration by means of stimulating the endogenous regenerative potential in situ is an attractive approach. This offers distinct advantages to stem cell implantation where the problems with engraftment and immune rejection are avoided. LÄS MER
25. Charting mast cell development in health and systemic mastocytosis
Sammanfattning : Hematopoietic stem and progenitor cells give rise to various blood and immune cells, including mast cells. In adults, bone marrow hematopoietic stem cells give rise to mast cell progenitors. These mast cell progenitors circulate in the peripheral blood and mature in peripheral tissues. LÄS MER