Sökning: "bone sialoprotein"

Hittade 5 avhandlingar innehållade orden bone sialoprotein.

  1. 1. Developing knee joint osteoarthritis: Clinical, radiographical and biochemical features

    Författare :Ingemar Petersson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone markers; cartilage markers; WOMAC; SF-36; function; health status quality-of-life; radiography; epidemiology; knee pain; Knee joint; osteoarthritis; bone scan; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

    Sammanfattning : The aim of this project was to study clinical, radiographical and biochemical features of developing, symptomatic knee osteoarthritis (OA) prospectively in individuals aged 35-54 from the general population. A questionnaire to a random sample of 2 000 individuals in the district of Laholm, Sweden, identified 279 individuals (15% of the population) with chronic (>3 months) knee pain. LÄS MER

  3. 2. Matrix resorption in endochondral bone growth : ultrastructural studies, with special attention to the chondroclast

    Författare :Joakim Nordahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :chondroclast; osteoclast; cartilage resorption; TRAP; cathepsin K; fibronectin; bone sialoprotein; osteopontin;

    Sammanfattning : A substantial amount of the calcified cartilage in the distal parts of the epiphyseal plate is resorbed during endochondral growth of long bones. However, the mechanisms involved in this process are still largely unknown. On the other hand, bone-resorption in the lower metaphysis has been thoroughly investigated. LÄS MER

  4. 3. Tissue destruction in arthritis : experimental studies

    Författare :Esbjörn Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Destruction of joint cartilage and bone is one of the most serious consequences of chronic arthritis. Clinically, the standard assessment of joint destruction is performed by radiography. LÄS MER

  5. 4. Primary osteoarthrosis in guinea pigs

    Författare :Edin de Bri; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The course of primary osteoarthrosis (OA) in Hartley guinea pigs, which spontaneously develop OA in their knee joints, was studied by stereology (quantitative morphology). Between 6 and 12 months of age, structural changes similar to those of human OA developed, predominantly in the central (non-meniscus-covered) medial condyle, while the lateral condyle remained unaffected. LÄS MER

  7. 5. Serum antibodies against Staphylococcus aureus antigens in healthy individuals and patients with invasive infections

    Författare :Patricia Colque-Navarro; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The present work aims to study the antibody responses against Staphylococcus aureus in health and in deep infections and is composed of six papers. We developed a sandwich enzyme immuno assay (EIA) with a detection limit for alpha-toxin at nanograms levels. LÄS MER