Sökning: "blood cerebrospinal fluid barrier function"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden blood cerebrospinal fluid barrier function.

1. 1. Zinc in cerebrospinal fluid and serum in some neurological diseases

   Författare :Ragnar Palm; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; zinc; copper; serum; cerebrospinal fluid; albumin; multiple sclerosis; epilepsy; phenytoin; blood brain barrier damage; subarachnoid haemorrhage.;

   Sammanfattning : The trace elements zinc and copper are essential components of many enzymes, some of which are of importance for the development and function of the central nervous system. Deficiency of the metals has been shown to lead to malformations and to the loss of myelin in animals. LÄS MER

3. 2. Clinical and etiological studies on dementia of Alzheimer type and multiinfarct dementia

   Författare :Gösta Bucht; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dementia of Alzheimer type; multiinfarct dementia; clinical studies; diagnosis; blood cerebrospinal fluid barrier function; cytogenetic changes; blood glucose; insulin secretion;

   Sammanfattning : 1. Clinical studies. Clinical diagnosis of dementia has been made largely on the basis of clinical findings supported by appropriate radiological and laboratory investigations. A minority of patients have treatable or reversible underlying causes for their dementing syndrome. LÄS MER

4. 3. Cardiac surgery and the brain - studies on cerebral blood flow autoregulation and mechanisms of cerebral injury

   Författare :Björn Reinsfelt; Göteborgs universitet; []
   Nyckelord :Cardiac surgery; cerrebral dysfunction; cardiopulmonary bypass; anaesthetics; aortic valve replacement; transcranial Doppler; cerebraospinal fluid; blood-brain barrier;

   Sammanfattning : Cardiac surgery and the brain - studies on cerebral blood flow autoregulation and mechanisms of cerebral injury Björn Reinsfelt Department of Anaesthesiology and Intensive Care, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Sweden Abstract Cerebral dysfunction (CD) occurs frequently after cardiac surgery with cardiopulmonary bypass (CPB). The main causes of CD are thought to be cerebral hypoperfusion, cerebral microembolisation , cerebral inflammation or disruption of the blood brain barrier (BBB). LÄS MER

5. 4. Blood Vessels, Biomarkers, and Broken Barriers: lnvestigations of the Brain Vasculature in Models of Neonatal Brain lnjuries

   Författare :E. Axel Andersson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neonatal brain injury; hypoxia ischemia; germinal matrix haemorrhage; blood brain barrier; tight‐junctions; blood vessels;

   Sammanfattning : Brain injury during the perinatal period can lead to lifelong impairment in cognitive and motor function, or an early death. Term neonatal encephalopathy and preterm germinal matrix haemorrhage are two conditions that can irreversibly injure the brain, but clinical tools for diagnosing and treating these pathologies are lacking. LÄS MER

7. 5. Studies of the Biology of Intrathecal Treatment in Progressive MS

   Författare :Joakim Bergman; Anders Svenningsson; A. Tommy Bergenheim; Jonathan D. Gilthorpe; Joachim Burman; Magnus Andersson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Progressive Multiple Sclerosis; intrathecal treatment; Ommaya reservoir; anti-CD20 therapy; microdialysis; cerebrospinal fluid; CNS compartments; Progressiv Multipel Skleros; intratekal behandling; Ommaya reservoar; anti-CD20 terapi; mikrodialys; ryggmärgsvätska; sektioner i centrala nervsystemet; Neurology; neurologi;

   Sammanfattning : Background: Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease, affecting the central nervous system (CNS). About 85% of afflicted present with a relapsing-remitting form of the disease (RRMS), for which a breakthrough in treatment was made in 2008 with rituximab, an antibody directed towards CD20, a surface antigen on B-cells. LÄS MER