Sökning: "biparatopic"

Hittade 2 avhandlingar innehållade ordet biparatopic.

1. 1. Bacterial display systems for engineering of affinity proteins

   Författare :Filippa Fleetwood; John Löfblom; Harald Kolmar; KTH; []
   Nyckelord :Combinatorial protein engineering; staphylococcal display; Affibody; biparatopic; VEGFR2; nanobody; E. coli display; autotransporter; Bioteknologi; Biotechnology;

   Sammanfattning : Directed evolution is a powerful method for engineering of specific affinity proteins such as antibodies and alternative scaffold proteins. For selections from combinatorial protein libraries, robust and high-throughput selection platforms are needed. LÄS MER

3. 2. Affibody Molecules Targeting VEGFR2 - Two Turns Off and Four Turns On

   Författare :Rezan Güler; John Löfblom; Stefan Ståhl; Dario Neri; KTH; []
   Nyckelord :Protein engineering; affibody molecules; VEGFR2; angiogenesis; Bioteknologi; Biotechnology;

   Sammanfattning : The notion of employing proteins as drugs traces back several decades. As recombinant DNA technology emerged, it became a powerful tool for the tailoring of protein traits via genetic approaches - so-called protein engineering. LÄS MER