Sökning: "betamethasone"

Visar resultat 6 - 10 av 12 avhandlingar innehållade ordet betamethasone.

  1. 6. Aspects of the inflammatory response and formation of polys in the nasal and sinus mucosa

    Författare :Tomas Norlander; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Experimental sinusitis was induced in rabbits by ostial occlusion, with or without subsequent inoculation of Streptococcus pneumoniae, Staphylococcus aureus or Bacteroides fragilis The general inflammatory response, including goblet cell differentiation and polyp formation, was morphologically investigated. Polyps were experimentally induced by a combining mechanical trauma the mucosa with infection or by injection of agarose or N-formyl-methionyl-leucyl-phenylalanine (FMLP) into the maxillary sinus. LÄS MER

  3. 7. Biological markers and treatment as prognostic factors in multiple myeloma

    Författare :Katarina Uttervall; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple myeloma (MM) is an incurable disease with an increasing number of treatment options. The introduction of what are called novel drugs (bortezomib, lenalidomide and thalidomide) was an important step. LÄS MER

  4. 8. Corticosteroids in advanced cancer : epidemiology, symptom relief and patient experiences

    Författare :Staffan Lundström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Corticosteroids; cancer; palliative care; anorexia; nausea; symptom assessment; existential;

    Sammanfattning : Cortisol is the principal circulating glucocorticoid in man and has a wide variety of effects in the body. In advanced metastatic cancer, glucocorticoids are used to alleviate symptoms such as anorexia, poor strength and poor wellbeing. The mechanisms behind the symptom relieving effects are still unclear. LÄS MER

  5. 9. Intracranial facial nerve lesion : experimental study on neural degeneration and its treatment

    Författare :Per Mattsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The aim of this thesis was to develop an experimental model that would generate extensive motor neuronal degeneration in adult rats, and furthermore to study mechanisms causing nerve cell death and effects of putative neuroprotective compounds. The facial nerve was chosen because it is well characterized and allows evaluation of functional recovery by analyzing vibrissae movements. LÄS MER

  7. 10. Nitric oxide and evaluation of different treatments in experimental colitis and inflammatory bowel disease

    Författare :Sofie Lundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder of unknown etiology of the gastrointestinal tract. Central features of IBD are increased nitric oxide (NO) generation in the gut lumen and dysfunction in regulation of leukocyte recruitment from the blood stream towards the affected tissue. LÄS MER