Sökning: "basal ganglia"

Visar resultat 1 - 5 av 99 avhandlingar innehållade orden basal ganglia.

1. 1. Computational Modeling of the Basal Ganglia : Functional Pathways and Reinforcement Learning

   Författare :Pierre Berthet; Anders Lansner; Kenji Doya; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; computational neuroscience; modelisation; reinforcement learning; basal ganglia; dopamine; datalogi; Computer Science;

   Sammanfattning : We perceive the environment via sensor arrays and interact with it through motor outputs. The work of this thesis concerns how the brain selects actions given the information about the perceived state of the world and how it learns and adapts these selections to changes in this environment. LÄS MER

3. 2. Beyond the basal ganglia

   Författare :Jorien m van der Burg; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hypothalamus; gastro-intestinal tract; Huntington s disease; metabolism; weight loss;

   Sammanfattning : Huntington’s disease (HD) is a fatal, hereditary disorder caused by a mutation in the gene encoding the protein huntingtin. Although mutant huntingtin is ubiquitously expressed throughout the body, HD research has mainly focused on the role of the basal ganglia. LÄS MER

4. 3. Subsystems of the basal ganglia and motor infrastructure

   Författare :Iman Kamali Sarvestani; Örjan Ekeberg; Jeanette Hällgren-Kotaleski; Christelle Baunez; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Basal Ganglia; Action Selection; Motor Learning; Tectum; Superior Colliculus; Mesencephalic Locomotor Region; Reticulospinal Neurons; Computational Models;

   Sammanfattning : The motor nervous system is one of the main systems of the body and is our principle means ofbehavior. Some of the most debilitating and wide spread disorders are motor systempathologies. In particular the basal ganglia are complex networks of the brain that control someaspects of movement in all vertebrates. LÄS MER

5. 4. Motion and Emotion : Functional In Vivo Analyses of the Mouse Basal Ganglia

   Författare :Emma Arvidsson; Åsa Wallén-Mackenzie; Cecilia Flores; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopamine; Basal Ganglia; Reward System; In Vivo Chronoamperometry; Optogenetics; Deep Brain Stimulation; Parkinson’s Disease; Addiction; Glutamate; Vesicular Glutamate Transporter; VGLUT2; Sex; Age; Subthalamic Nucleus; Striatum; Nucleus Accumbens; Ventral Tegmental Area;

   Sammanfattning : A major challenge in the field of neuroscience is to link behavior with specific neuronal circuitries and cellular events. One way of facing this challenge is to identify unique cellular markers and thus have the ability to, through various mouse genetics tools, mimic, manipulate and control various aspects of neuronal activity to decipher their correlation to behavior. LÄS MER

7. 5. Organization of basal ganglia circuits

   Författare :Daniel Fürth; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Anatomical regions and how we define boundaries between and within structures in the brain put a constraint on our understanding of the brain. More than a century of research on the brain has revealed its fundamental organization to be based on single nerve cells communicating through electrical signals over chemical synapses. LÄS MER