Sökning: "barcoding"

Visar resultat 1 - 5 av 33 avhandlingar innehållade ordet barcoding.

1. 1. Exploring human variations by droplet barcoding

   Författare :Pontus Höjer; Afshin Ahmadian; Pelin Sahlén; Lars Feuk; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; droplets; linked-read sequencing; DNA barcoding; proteomics; genomics; single cell; single extracellular vesicle; single exosome; pipelines; Biotechnology; Bioteknologi;

   Sammanfattning : Biological variations are being explored at ever-increasing rates through the rapid advancement of analytical techniques. Techniques like massively parallel sequencing empower scientists to accurately differentiate individuals’ genetic compositions, cellular functionalities, and healthy tissue from diseased. LÄS MER

3. 2. Proximity Ligation and Barcoding Assays : Tools for analysis of proteins and protein complexes

   Författare :Di Wu; Masood Kamali-Moghaddam; Ulf Landegren; Ola Söderberg; Jörg Hoheisel; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proximity ligation assay; proximity barcoding assay; sensitive; in situ; multiplex; profiling; amyloid-beta; MARK; tau; CSF; biomarker; protein complexes; Alzheimer’s disease; amyotrophic lateral sclerosis; Molekylär medicin; Molecular Medicine;

   Sammanfattning : Proteins are fundamental structural, enzymatic and regulatory components of cells. Analysis of proteins, such as by measuring their concentrations, characterizing their modifications, and detecting their interactions, provides insights in how biological systems work physiologically or pathologically at the molecular level. LÄS MER

4. 3. Charting Insect Diversity

   Författare :Dave Karlsson; Fredrik Ronquist; Torbjørn Ekrem; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; insect faunas; biological inventories; citizen science; DNA barcoding; morphotype barcoding; Systematic Zoology; zoologisk systematik och evolutionsforskning;

   Sammanfattning : Background: Despite Sweden's rich legacy in entomology, a significant portion of its insect fauna remains poorly studied. Addressing this and other biodiversity knowledge gaps, the Swedish government unveiled the Swedish Taxonomy Initiative (STI) in 2002, with the ambitious goal of documenting and scientifically describing all multicellular species in the country. LÄS MER

5. 4. Taking a Bite out of Diversity - Taxonomy and systematics of biting midges

   Författare :Jonas Strandberg; Kjell Arne Johanson; Urban Olsson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ceratopogonidae; Dasyhelea; barcoding; COI; phylogeny Sweden; Forcipomyia; Bezzia; Palpomyia; Degen1; Systematic Zoology; zoologisk systematik och evolutionsforskning;

   Sammanfattning : The biting midges (family Ceratopogonidae) is one of the most species rich amongst the biting flies (Diptera) and has been recorded from most parts of the world. The species are mostly known for their capability to act as vectors for several important diseases, which have helped in shaping the focus to one of its genera, Culicoides Latreille, 1809. LÄS MER

7. 5. It Takes Two to Tango : Bacterial heterogeneity and host cell features govern Salmonella infection

   Författare :Viktor Ek; Mikael E. Sellin; Francisco García del Portillo; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Salmonella; swimming; swim pattern; targetting; virulence; invasion; host-pathogen interactions; epithelium; epithelial cells; macrophages; monocytes; monolayer; flagella; genome; genetic; barcoding; discreet-invasion; shape; morphology; antibiotics; persistence; Mikrobiologi; Microbiology;

   Sammanfattning : Salmonella enterica serovar Typhimurium (S.Tm) causes enterocolitis with significant worldwide morbidity and mortality. The general aim of this thesis is to investigate variation in host cell invasion mechanisms used by S.Tm across different host cell contexts, as well as the influence of bacterial cell-cell heterogeneity on invasion-relevant S. LÄS MER