Sökning: "background radiation"

Visar resultat 1 - 5 av 153 avhandlingar innehållade orden background radiation.

  1. 1. Optimizing experimental radioimmunotherapy : investigating the different mechanisms behind radiation induced cell deaths

    Författare :Theres Lindgren; David Eriksson; Torgny Stigbrand; Bo Stenerlöw; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitotic catastrophe; senescence; cell cycle checkpoint; apoptosis; radiation; gene expression; p53; immunologi; Immunology; radiofysik; radiation physics;

    Sammanfattning : Background. Radiation therapy is an important treatment regimen for malignant disease. Radiation therapy uses ionizing radiation to induce DNA damage in tumor cells in order to kill them. LÄS MER

  2. 2. Role of MTH1 and MYH proteins in genotoxic effects of radiation

    Författare :Sara Shakeri Manesh; Siamak Haghdoost; William F. Morgan; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MTH1; MYH; gamma radiation; UV radiation; oxidative stress; low dose rate ionizing radiation; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Humans are constantly exposed to different types of radiations. It has been suggested that low dose and low dose rate of γ-radiation as well as ultra violet A (UVA) induce oxidative stress in cells that may promote mutations. LÄS MER

  3. 3. Oxidized nucleotides as a predictor of radiation sensitivity

    Författare :Ali Pour Khavari; Siamak Haghdoost; Marie Öhman; Anders Nilsson; Bo Stenerlöw; Neus Visa; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 8-oxo-dG; Radiation; Sensitivity; Oxidized; Nucleotides; ROS; NOS; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : The direct and indirect effects of IR can lead to DNA damage and activation of DNA repair. The indirect effects of ionizing radiation mediated by reactive oxygen species (ROS) which produced through radiolysis of water and if not taken care of by the antioxidant system, can also give rise to oxidative stress. LÄS MER

  4. 4. Modelling late toxicity in hypofractionated radiation therapy

    Författare :Niclas Pettersson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hypofractionation; normal tissue complication probability; modelling; linear-quadratic model; fractionation sensitivity; late toxicity; radiation-induced rib fracture; genitourinary toxicity; stereotactic body radiation therapy; high-dose-rate brachytherapy; multimodality radiation therapy; patient-reported outcomes; prostate cancer; nsclc;

    Sammanfattning : In hypofractionated radiation therapy (RT), the treatment is delivered by few fractions with high doses per fraction. This is in contrast to conventionally fractionated RT where the total dose is delivered in many fractions with low doses per fraction. LÄS MER

  5. 5. Orphan source detection in mobile gamma-ray spectrometry - Improved techniques for background assessment

    Författare :Peder Kock; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gamma spectrometry; airborne; car-borne; radioactive; orphan sources; hypothesis testing; background radiation;

    Sammanfattning : Hazardous radioactive sources out of regulatory control are referred to as orphan sources. Focussing on gamma-emitting orphan sources, this thesis describes methods that can be used in mobile gamma-ray spectrometry to perform real-time discrimination between an actual source signal and the signal due to the natural radiation background. LÄS MER