Sökning: "axonal guidance"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden axonal guidance.
1. Controlled axonal outgrowth and cell reactions to nanostructures
Sammanfattning : The interface between living cells and artificial surfaces are highly relevant for biomedical applications such as implants and organized cell growth for tissue reconstruction as well as for basic science purposes. In the present thesis, we have studied axonal guidance on various nano-patterned surfaces such as polymethyl-meth-acrylate, porous silicon and on magnetically aligned Ni nanowires. LÄS MER
2. Studies on Peripheral Nerve Regeneration: Microdispensing, Neurite Guidance and Galectins
Sammanfattning : The present thesis describes development of a microdispenser-based technique to create of protein patterns for neurite guidance. The same technique was also developed to allow direct positioning of dissociated cells, including neurons, on cell culture substrates. Finally the role of galectin-3 and 8 during nerve regeneration was investigated. LÄS MER
3. Machine Learning Techniques with Specific Application to the Early Olfactory System
Sammanfattning : This thesis deals with machine learning techniques for the extraction of structure and the analysis of the vertebrate olfactory pathway based on related methods. Some of its main contributions are summarized below. LÄS MER
4. Nanowires for Cell Research
Sammanfattning : This study explores the interaction between living biological cells and semiconductor nanowires. Biological cells are highly complex and dynamic entities, every one of them with individual characteristics and a high degree of internal and external communication. LÄS MER
5. Molecular mechanisms of nerve-tumor interactions : the intersection of cancer and neurodevelopment
Sammanfattning : A wide range of cancers throughout the body are characterized by high nerve density and invasion of cancer cells within the nerves, a process called perineural invasion (PNI). Work in the field has shown that blocking nerves in organs with tumors leads to improved disease outcomes suggesting that finding ways to block tumor nerves could lead to new treatment approaches. LÄS MER