Sökning: "anti-CCP"

Visar resultat 6 - 10 av 16 avhandlingar innehållade ordet anti-CCP.

1. 6. Autoantibodies and genetic variation in rheumatoid arthritis : aspects on susceptibility and disease course

   Författare :Alf Kastbom; Thomas Skogh; Peter Söderkvist; Alex Karlsson-Parra; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; autoantibodies; single-nucleotide polymorphisms; disease course; Rheumatology; Reumatologi;

   Sammanfattning : Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and subsequent destruction of synovial joints. Although its causes remain largely unknown, a substantial genetic contribution is known to exist. LÄS MER

3. 7. Understanding juvenile idiopathic arthritis : a multidimensional approach

   Författare :Raya Saleh; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The overarching objective of this doctoral thesis is to enhance the understanding of Juvenile Idiopathic Arthritis (JIA), a complex autoimmune disease affecting children. With the aim of filling the knowledge gaps in JIA, we conducted a comprehensive study on biomarkers with distinct biological implications, including genetic variations, autoantibodies, and plasma and synovial fluid proteins, in individuals with JIA and controls. LÄS MER

4. 8. A population-based study on early arthritis in southern Sweden : Incidence, preceding infections, diagnostic markers and economic burden

   Författare :Maria Söderlin; Marjatta Leirisalo-Repo; Thomas Skogh; Tore Kvien; Linköpings universitet; []
   Nyckelord :Arthritis diagnosis; arthritis economics; Biological markers blood; Extracellular matrix proteins blood; Cost of illness; MEDICINE; MEDICIN;

   Sammanfattning : The total annual incidence of arthritis in this prospective cross-sectional study on adults was 115/100 000. The annual incidence of rheumatoid arthritis (RA) was 24/100 000, 29/100 000 for women, and 18/100 000 for men. For reactive arthritis (ReA) the annual incidence was slightly higher, 28/100 000, and for undifferentiated arthritis 41/100 000. LÄS MER

5. 9. Early rheumatoid arthritis : biomarkers and hormonal factors in relation to disease progression

   Författare :Antonia Boman; Solbritt Rantapää-Dahlqvist; Ewa Berglin; Gerd-Marie Alenius; Mikael Brink; Heidi Kokkonen; Inger Gjertsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Early rheumatoid arthritis; biomarker; ACPA; RANKL; disease activity; radiological destruction; cardiovascular events; hormonal factors; reumatologi; rheumatology;

   Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, affecting approximately 0.5 to 1% of the adult population. Although the aetiology is not fully known, a complex interaction between genetic, environmental and stochastic factors is thought to trigger the pathogenic mechanisms. LÄS MER

7. 10. Disease activity, function and costs in early rheumatoid arthritis

   Författare :Eva Hallert; Thomas Skogh; Jan Persson; Ronald van Vollenhoven; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antirheumatic agents; Rheumatoid arthritis; Cost of illness; Health care costs; Joints physiopathology; Sex factors; Rheumatology; Reumatologi;

   Sammanfattning : Rheumatoid arthritis (RA) is a major cause of progressive joint damage and disability, and is associated with decline in quality of life, reduced ability to work and increased health care utilisation. The economic consequences of the disease are substantial for the individuals and their families and for the society as a whole. LÄS MER