Sökning: "alveolar immune response"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden alveolar immune response.

1. 1. The Immune Response to One-Lung Ventilation : Clinical and Experimental Studies

   Författare :Thomas Schilling; Göran Hedenstierna; Hans Hedenström; Thomas Hachenberg; Sven-Erik Ricksten; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; Medical laboratory science; Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

   Sammanfattning : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. LÄS MER

3. 2. Innate immune cell response in sepsis

   Författare :Yongzhi Wang; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; abdominal sepsis; neutrophil; monocyte; platelet; coagulation; lung;

   Sammanfattning : Leukocyte recruitment is known to be a key feature at sites of inflammation and important in the combat against infectious agents. However, the mechanisms of leukocyte recruitment in the pulmonary microvasculature in response to local and systemic inflammation remain elusive. LÄS MER

4. 3. Apoptotic neutrophils enhance the immune response against Mycobacterium tuberculosis

   Författare :Alexander Persson; Olle Stendahl; Per-Arne Oldenborg; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

   Sammanfattning : Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, a disease that for years was considered to belong of the past, but tuberculosis is back causing over 2 million deaths per year. The infection can be dormant for decades and an active immune response can prevent the infection from progressing into active disease. LÄS MER

5. 4. Remote Ischemic Preconditioning and its Effects on the Respiratory System

   Författare :Astrid Bergmann; Anders Larsson; Göran Hedenstierna; Thomas Hachenberg; Ola Winsö; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; one-lung ventilation; ventilation-induced lung injury; alveolar immune response; remote ischemic preconditioning; exhaled nitric oxide; animal model; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : Mechanical ventilation in itself can lead to pulmonary damage, and one-lung ventilation (OLV), necessary for thoracic surgery, accentuates this injury. Remote ischemic preconditioning (RIP) is a potential tool to reduce lung injury after mechanical ventilation, including OLV.  However, current data on pulmonary RIP-effects are contradictory. LÄS MER

7. 5. Mycobacterium tuberculosis and HIV coinfection : Effects on innate immunity and strategies to boost the immune response

   Författare :Anna-Maria Andersson; Robert Blomgran Julinder; Marie Larsson; Olle Stendahl; Susanna Brighenti; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : Tuberculosis (TB) still remains a big threat today, being the leading cause of death by a single infectious agent. The TB epidemic is fueled by HIV along with the increasing drug-resistance which prolongs the already long treatment duration and decreases the success rate for curing TB. LÄS MER