Sökning: "allergic heredity"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden allergic heredity.

1. 1. Microbial and maternal influences on allergic sensitization during childhood: defining a role for monocytes

   Författare :Shanie Saghafian Hedengren; Eva Sverremark-Ekström; Susan Prescott; Stockholms universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; allergic sensitization; maternal allergy; Toll-like receptor; p38-MAPK; IL-6; Epstein-Barr virus; early-life microbial exposure; NK cells; IFN-γ; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : Allergic diseases are influenced by genetics and the environment. Maternal allergy appears to confer a higher risk for allergic sensitization than paternal allergy, suggesting an in utero influence. LÄS MER

3. 2. Infant gut microbiota, immune responses and allergic disease during childhood

   Författare :Maria A. Johansson; Eva Sverremark-Ekström; Christina West; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

   Sammanfattning : The early-life microbiota is important for postnatal immune maturation and implied in immune mediated diseases. The aim of this work was to study specific species of bacteria in the gut microbiota and relate them to immune function and allergic disease during childhood. LÄS MER

4. 3. Allergic diseases and bronchial hyperreactivity in Estonian children in relation to environmental influences

   Författare :Marie Vasar; Kajsu Juntunen-Backman; Lii Jannus-Pruljan; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : This thesis is based on the cross-sectional and prospective study of Estonian children. The aim of this thesis was to assess the prevalence of allergic diseases and respiratory symptoms in Estonian schoolchildren and in young children, to study environmental risk factors for allergic diseases and repiratory symptoms. LÄS MER

5. 4. Maternal immune characteristics and innate immune responses in the child in relation to allergic disease

   Författare :Petra Amoudruz; Eva Sverremark-Ekström; Zsolt Szépfalusi; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi; immunologi; Immunology;

   Sammanfattning : The mechanistic factors responsible for the increase in allergic diseases are still not fully understood, but a reduced microbial stimulation seems to be one of the key issues. Research is now aiming at investigating the relationship between the innate immune system, involving the toll-like receptors, and allergy development. LÄS MER

7. 5. Cytokine profiles, infections and IgE sensitisation in childhood

   Författare :Caroline Nilsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Allergy; allergic heredity; childhood; cytokines; IgE-sensitisation; Epstein-Barr virus; interleukin-12; viral infections.;

   Sammanfattning : Background: The etiologic factors behind development of lgE-mediated allergy are incompletely understood although the interaction between allergic heredity and exposure to various environmental factors seems to be most important. Objective: The overall aim of this thesis was to study the associations between allergic heredity, environmental factors like viral infections and lgE sensitisation and the development of allergic diseases during childhood. LÄS MER