Sökning: "adrenal steroidogenesis"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden adrenal steroidogenesis.
1. Enzymatic Regulation of Steroidogenesis and Nuclear Receptor Activation : Special Focus on Vitamin D and Sex Hormones
Sammanfattning : Enzyme-catalyzed reactions are important to regulate steroidogenesis and nuclear receptor activation. The present investigation examines the role of steroid metabolism catalyzed by CYP7B1 for regulation of hormone receptor activation and the effects of vitamin D on enzymatic regulation of steroidogenesis. LÄS MER
2. New Insights in Adrenal Tumourigenesis
Sammanfattning : Unilateral cortisol producing adenoma (CPA) is the most common cause of ACTH-independent Cushing’s syndrome and is surgically curable. On the other hand, adrenocortical carcinomas (ACCs) are rare and aggressive tumours. LÄS MER
3. Equine glutathione transferase A3-3 : an efficient steroid isomerase
Sammanfattning : Glutathione transferases (GSTs) comprise a superfamily of enzymes prominently involved in detoxication by making toxic electrophiles more polar and therefore more easily excretable. However some GSTs have developed alternative functions. LÄS MER
4. In vitro and in vivo studies on the toxicology of di-n-butyl phthalate (DBP) : Effects on reproductive, endocrine, and immune systems
Sammanfattning : Chemical pollution is an increasing societal problem and has a major impact on human and environmental health. One important source of chemical pollution is plastic, which contains many different compounds with often largely unknown hazards. LÄS MER
5. Cytochrome P-450 dependent monooxygenases in the mammalian adrenal cortex : properties and role in steroidogenesis and metabolism of polycyclic aromatic hydrocarbons
Sammanfattning : .... LÄS MER