Sökning: "accelerated fractionation"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden accelerated fractionation.

  1. 1. Searching for the optimal radiotherapy treatment time, dose and fractionation - the role of hypoxia and reoxygenation : A modelling study

    Författare :Emely Lindblom; Iuliana Toma-Dasu; Ingmar Lax; Ludvig Paul Muren; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hypoxia; Reoxygenation; SBRT; Fractionation; Medical Radiation Physics; medicinsk strålningsfysik;

    Sammanfattning : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. LÄS MER

  2. 2. Radiotherapy for head and neck cancer : costs and benefits of time, dose and volume

    Författare :Karin Söderström; Björn Zackrisson; Werner Dubrowsky; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiotherapy; head and neck cancer; adjuvant treatment; accelerated fractionation; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Sammanfattning : Background In the treatment of head and neck cancers (HNCs), radiotherapy (RT) has the advantage of organ preservation compared to surgery. However, treatment toxicities associated with RT can affect important functions for everyday life, both in the acute and late stage. LÄS MER

  3. 3. Time, dose and fractionation: accounting for hypoxia in the search for optimal radiotherapy treatment parameters

    Författare :Emely Kjellsson Lindblom; Iuliana Toma-Dasu; Peter Wersäll; David J Carlson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hypoxia; radiobiological modelling; radiotherapy; functional imaging; Medical Radiation Physics; medicinsk strålningsfysik;

    Sammanfattning : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. LÄS MER

  4. 4. Rapid sample preparation and bioanalytical techniques for efficient screening of organic pollutants in the environment

    Författare :Malin Nording; Peter Haglund; Ron Hoogenboom; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; accelerated solvent extraction; CAFLUX; food; immunoassay; PAH; PCDD; PCDF; pressurized liquid extraction; soil; CALUX; cell-based bioassay; chemically activated fluorescent gene expression; chemically activated luciferase gene expression; dioxin; ELISA; enzyme-linked immunosorbent assay; feed; Environmental chemistry; Miljökemi;

    Sammanfattning : Large numbers of samples often need to be prepared and analysed in surveys of organic pollutants in the environment, but while the methods commonly used in such surveys can provide abundant detail they are generally costly, time-consuming and require large amounts of resources, so there is a need for simpler techniques. The work underlying this thesis assessed the potential utility of more convenient sample preparation and bioanalytical techniques for rapidly screening various environmental matrices that could be useful complements to higher resolution methods. LÄS MER

  5. 5. Analysis of PAHs and their transformations products in contaminated soil and remedial processes

    Författare :Staffan Lundstedt; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; polycyclic aromatic hydrocarbons; PAHs; degredation; transformation; formation; accumulation; oxidation products; metabolites; oxogenated polycyclic aromatic hydrocarbons; oxy-PAHs; soil; gasworks; remediation; bioremediation; bioslurry; wood-rotting fungi; Fenton´s reagent; avaliability; bioavaliability; chemical analysis; extraction; pressurized liquid extraction; PLE; accelerated solvent extraction; ASE; Miljökemi; Environmental chemistry; Miljökemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : Soil that is heavily contaminated with polycyclic aromatic hydrocarbons (PAHs) is often found at the sites of former gasworks and wood-impregnation plants. Since PAHs are toxic these sites represent a hazard to human health and the environment, and therefore they need to be treated, preferably by a method that destroys the contaminants, and thus eliminates the problem permanently. LÄS MER