Sökning: "Ville Wallenius"
Hittade 5 avhandlingar innehållade orden Ville Wallenius.
1. Hormonal regulation of liver and tumor growth
Sammanfattning : The aims of this thesis were to investigate the regulatory functions of interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-a) on liver growth, and the importance of hepatocyte growth factor (HGF) and the HGF receptor (Met) for growth of mesenchyme-derived tumors. The studies on different types of liver growth, measured as weight, DNA and protein content, and DNA synthesis, were performed on mice lacking the IL-6 or the TNF receptor-1 gene back-crossed to the C57bl/6 strain. LÄS MER
2. Changes in Gastrointestinal Function and Patient-scored Symptoms after Bariatric Surgery
Sammanfattning : The obesity pandemic is rapidly increasing. Individuals with obesity are affected by obesity-related comorbidities, reduced life expectancy, and reduced quality of life. The most effective treatment for obesity and its comorbidities is bariatric surgery, restoring the physical component of quality of life. LÄS MER
3. The Role of Interleukin-6 in the Febrile Response
Sammanfattning : Everyone who has been exposed to influenza or a bacterial infection knows how it feels to be sick. Apart from not being willing to participate in social activities, losing your appetite and experiencing pain, you have also most likely suffered from increased body temperature which defines fever, one of the most prominent signs of an acute ongoing infection. LÄS MER
4. Bariatric Surgery : Outcomes after Gastric Bypass and Duodenal Switch
Sammanfattning : Obesity is associated with increased morbidity and mortality. A BMI >40 kg/m2 shortens life expectancy by about 10 years. The obesity related comorbidities diabetes, hypertension, dyslipidemia and sleep apnea contributes to the increased risk of cardiovascular events. There is also an increased risk of some forms of cancer (e. LÄS MER
5. Register-based studies on cholecystectomy : Quality of life after cholecystectomy, and cholecystectomy incidence and complications after gastric bypass
Sammanfattning : Cholecystectomy (removal of the gallbladder) is standard surgical treatment for patients with symptomatic gallstone disease, albeit not without complications. Assessing the impact on quality of life is crucial for appropriate cholecystectomy patient selection, and the Gastrointestinal Quality of Life Index (GIQLI) is a 36-item questionnaire validated for this purpose. LÄS MER