Sökning: "VIP."

Visar resultat 1 - 5 av 84 avhandlingar innehållade ordet VIP..

1. 1. The neuropeptide VIP and the IL-6 family of cytokines in bone : effects on bone resorption, cytokine expression and receptor signalling in osteoblasts and bone marrow stromal cells

   Författare :Emma Persson; Ulf Lerner; Andreas Kindmark; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; osteoblast; bone resorption; cytokines; IL-6; neuropeptides; VIP; transcription factor; Cell biology; Cellbiologi;

   Sammanfattning : Bone tissue is continuously degraded and rebuilt to respond to the needs of the body. Cells of the osteoblast lineage are responsible for the formation of bone, whereas the resorption of bone tissue is carried out by osteoclasts. LÄS MER

3. 2. The neuronal and non-neuronal substance P, VIP and cholinergic systems in the colon in ulcerative colitis

   Författare :Maria Jönsson; Sture Forsgren; Örjan Norrgård; Johan D Söderholm; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ulcerative colitis; neuropeptides; substance P; VIP; non-neuronal cholinergic system; Anatomy; Anatomi; Surgery; Kirurgi; anatomi; Human Anatomy;

   Sammanfattning : Ulcerative colitis (UC) is a chronic relapsing inflammatory bowel disease. Neuropeptides, especially vasoactive intestinal peptide (VIP) and substance P (SP), have long been considered to play key roles in UC. Among other effects, these neuropeptides have trophic and growth-modulating as well as wound-healing effects. LÄS MER

4. 3. Novel variable influence on projection (VIP) methods in OPLS, O2PLS, and OnPLS models for single- and multi-block variable selection : VIPOPLS, VIPO2PLS, and MB-VIOP methods

   Författare :Beatriz Galindo-Prieto; Johan Trygg; Lennart Eriksson; Paul Geladi; Olav M. Kvalheim; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Variable influence on projection; VIP; MB-VIOP; orthogonal projections to latent structures; OPLS; O2PLS; OnPLS; variable selection; variable importance in multiblock regression; Computer Science; datalogi;

   Sammanfattning : Multivariate and multiblock data analysis involves useful methodologies for analyzing large data sets in chemistry, biology, psychology, economics, sensory science, and industrial processes; among these methodologies, partial least squares (PLS) and orthogonal projections to latent structures (OPLS®) have become popular. Due to the increasingly computerized instrumentation, a data set can consist of thousands of input variables which contain latent information valuable for research and industrial purposes. LÄS MER

5. 4. Neuroimmune Interactions of Enteric Neurons and Mast Cells: Friends or Foes?

   Författare :Elin Sand; Neurogastroenterologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enteric neurons; ischemia; VIP; mast cells; CRF;

   Sammanfattning : Psychological distress or physical strain lead to reduced blood flow in the intestine since other organs are prioritised. One aim of this thesis was to investigate how ischemia followed by reperfusion affects the large intestine and the enteric nervous system (ENS). LÄS MER

7. 5. Intestinal barrier function in health and disease

   Författare :Pernilla Nejdfors; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; VIP.; PACAP; secretion; ion transport; urine reservoir; radiation therapy; ulcerative colitis; macromolecules; dextran; mannitol; Ussing chamber; Intestinal permeability; mucosa; Animal physiology; Djurfysiologi; Physiology; Fysiologi;

   Sammanfattning : The intestinal epithelium has the dual function of absorbing nutrients and water as well as being a barrier to potentially harmful substances such as macromolecules and bacteria. In the present thesis the barrier function of the intestinal mucosa was studied in vitro in Ussing diffusion chambers. LÄS MER