Sökning: "Unsaturated ketones"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Unsaturated ketones.

  1. 1. Development of organocatalytic asymmetric transformations

    Författare :Ismail Ibrahem; Armando Cordova; Stephen Hanessian; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Asymmetric Catalysis; α-amino acids; Aldehydes; Ketones; α-Aminomethylation; Aziridination; Hydrophosphination; Diarylprolinol; Proline derivatives; Organic synthesis; Organisk syntes; Organic Chemistry; organisk kemi;

    Sammanfattning : The ability of amino acids and amino acid derivatives to mediate various organocatalytic asymmetric transformations has been investigated and applied in the development of various reactions. This work describes the development of a direct catalytic asymmetric α-aminomethylation of ketones and aldehydes, a catalytic asymmetric aziridination, hydrophosphination and amination of α,β-unsaturated aldehydes. LÄS MER

  3. 2. Optimering i organisk syntes : betingelser, system, syntesvägar

    Författare :Lars Hansson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optimization; Response surface method; PLS method; Silylation; Enolether; Unsaturated ketones; Diketones; Geosmin synthesis; Onepot procedure;

    Sammanfattning : This thesis deals with different optimization problems encountered in organic synthesis. The use of response surface, sequential simplex and PLS techniques, for simultanious optimization of yield and suppression of side reactions is investigated. This is illustrated by an example of enamine synthesis, were a side reaction was a serious problem. LÄS MER

  4. 3. New Applications of Monoorganocopper/Iodotrimethylsilane Reagents in Conjugate Additions

    Författare :Magnus Eriksson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; beta-unsaturated; halosilane; conjugate addition; alpha; copper iodide; copper acetylides; organocopper; iodotrimethylsilane; Claisen rearrangement;

    Sammanfattning : The thesis reports new applications of monoorganocopper compounds, RCu(LiI), and iodotrimethylsilane in conjugate additions. The present investigation demonstrates conjugate addition of alkylcopper compounds and iodotrimethylsilane to reactive .alpha.,. LÄS MER

  5. 4. Metal Mediated Synthesis. Synthetic and Mechanistic Investigations of Conjugate Addition and Reductive Amination

    Författare :Anders Johansson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; halosilane; all-trans-geranylgeraniol; copper reagent; primary amines; S -geranylcitronellol; iminium salt; alfa; cuprate; beta-unsaturated; lithium iodide; borane dimethyl sulfide complex; reductive amination; conjugate addition;

    Sammanfattning : The thesis is divided into two separate parts, one treating conjugate addition and the other reductive aminations. The first part of the thesis is concerned with organocopper promoted conjugate addition to .alfa.,. LÄS MER

  7. 5. Synthetic studies of nitrogen containing heterocycles, particularly pyrazole and benzotriazine derivatives

    Författare :Azadeh Nakhai; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Pyrazole; indazole; tetrahydroindazoles; hexahydroindazoles; alpha; beta-unsaturated ketones; dihydropyrazolone; 3; 3 -biindolyl; 3; 3 -biindazolyl; o-azidobenzonitriles; benzotriazine; aryl-triazene;

    Sammanfattning : This thesis will mainly focus on the chemistry of nitrogen containing heterocyclic compounds, particularly pyrazole and benzotriazine and related ring systems to these compounds. The first part includes a short introduction to biologically important compounds as well as a description of reactivity and chemistry of benzo[c]pyrazole (indazole) and its derivatives. LÄS MER