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1. 1. The Carboxyl Ester Lipase Gene. Organization, Evolution and Transcriptional Regulation in Exocrine Pancreas and Mammary Gland

   Författare :Ulf Lidberg; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NF-1; pseudogene; evolution; pancreas; carboxyl ester lipase; regulation; duplication; promoter; enhancer; locus; gene structure; mammary gland;

   Sammanfattning : The carboxyl ester lipase (CEL) is an important enzyme for the intestinal absorption of dietary lipids. In humans the gene is highly expressed in exocrine pancreas and in the lactating mammary gland. It is secreted in an inactive form and becomes activated by bile salts in the intestine. LÄS MER