Sökning: "Ulf Brunk"
Hittade 4 avhandlingar innehållade orden Ulf Brunk.
1. Lysosomes and residual bodies in neurons and in vitro cultivated glia cells
Sammanfattning : .... LÄS MER
2. Oxidative stress-related damage of retinal pigment epithelial cells : possible protective properties of autophagocytosed iron-binding proteins
Sammanfattning : Oxidative stress is a major pathogenic factor in the development of age-related macular degeneration (AMD), which is the most common cause of severe central visual impairment in the elderly population in the western world.It is believed that the degenerative process starts in the retinal pigment epithelium (RPE). LÄS MER
3. Lysosomal stability under the influence of oxidative stress and lipofuscin accumulation
Sammanfattning : The lysosome is the cellular organelle responsible for degradation and recycling of macromolecules through hetero- and autophagocytosis. It is generally considered a stable organelle that breaks down only late during cellular degeneration. LÄS MER
4. Ageing-associated changes of lysosomal compartment : implications on cellular functions
Sammanfattning : The lysosomal compartment is a major site for intracellular degradation. Lysosomal degradation of the cell’s own constituents, so-called autophagy, not only provides a cell with nutrients, but also removes damaged and potentially dangerous endogenous structures, thus securing intracellular homeostasis. LÄS MER