Sökning: "Torben Österlund"

Hittade 2 avhandlingar innehållade orden Torben Österlund.

  1. 1. Structure-function relationships of hormone-sensitive lipase

    Författare :Torben Österlund; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteins; mutagenesis; domain; fold; catalytic triad; lipase; structure; enzymology; Proteiner; enzymologi;

    Sammanfattning : The primary role of hormone-sensitive lipase (HSL), an 84 kDa enzyme of 768 amino acids (in the rat protein), is to hydrolyse stored triacylglycerols in adipocytes of white adipose tissue. Catecholamines and insulin regulate lipolysis through cellular signalling. LÄS MER

  3. 2. Prognostic and Predictive Factors in Metastatic Colorectal Cancer

    Författare :Emerik Österlund; Tobias Sjöblom; Bengt Glimelius; Peter Nygren; Torben Frøstrup Hansen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metastatic colorectal cancer; RAS mutations; BRAF mutations; biomarkers; outcome;

    Sammanfattning : The outcome for metastatic colorectal cancer (mCRC) patients has improved substantially in recent decades. This has chiefly been observed in study populations, and predominantly in left-sided primary tumours, which is why we wanted to study if and how survival has improved in the background population. LÄS MER