Sökning: "Tommi Ratilainen"

Hittade 2 avhandlingar innehållade orden Tommi Ratilainen.

1. 1. Thermodynamics of Peptide Nucleic Acid Interactions with DNA

   Författare :Tommi Ratilainen; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; thermodynamics; enthalpy-entropy compensation; ionic strength; nucleic acids; fluorescence energy transfer; PNA; calorimetry; sequence-specific binding;

   Sammanfattning : Peptide Nucleic Acid (PNA) is a DNA mimic with the natural nucleobases attached to a charge-neutral pseudopeptide backbone. It has remarkably strong and sequence-specific binding affinity to natural nucleic acids (DNA and RNA), mainly attributed to the lack of charge in the PNA backbone. LÄS MER

3. 2. Thermodynamics of PNA-DNA interactions studied by spectroscopic and calorimetric methods

   Författare :Tommi Ratilainen; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : .... LÄS MER