Sökning: "TYROSINE"

Visar resultat 1 - 5 av 671 avhandlingar innehållade ordet TYROSINE.

1. 1. Trapping Tyrosine Z : Exploring the Relay between Photochemistry and Water Oxidation in Photosystem II

   Författare :Johannes Sjöholm; Stenbjörn Styring; Fikret Mamedov; A. William Rutherford; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Photosystem II; Tyrosine Z; EPR; proton-coupled electron transfer; hydrogen bond; pH;

   Sammanfattning : Photosystem II is unique! It remains the only enzyme that can oxidize water using light as energy input. Water oxidation in photosystem II is catalyzed by the CaMn4 cluster. The electrons extracted from the CaMn4 cluster are transferred to P680+ via the tyrosine residue D1-Tyr161 (YZ). LÄS MER

3. 2. The Tyrosine Kinase GTK : Signal Transduction and Biological Function

   Författare :Cecilia Annerén; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Protein tyrosine kinases; GTK; SHB; proliferation; survival; differentiation; β cells; pancreatectomy; cytokines; diabetes; PC12 cells; NGF; streptozotocin; focal adhesion kinase; RAP1; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

   Sammanfattning : Protein tyrosine kinases play an important role in the regulation of various cellular processes such asgrowth, differentiation and survival. GTK, a novel SRC-like cytoplasmic tyrosine kinase, was recently cloned from a mouse insulinoma cell line and the present work was conducted in order to find a biological function of GTK in insulin producing and neuronal cells. LÄS MER

4. 3. Mechanistic Studies on Proton-Coupled Electron Transfer from Tyrosine and Tryptophan Derivatives

   Författare :Astrid Nilsen-Moe; Leif Hammarström; Pia Ädelroth; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proton-Coupled Electron Transfer; PCET; Tyrosine; Tryptophan; Amino Acid Radicals; Transient Absorption; Chemistry with specialization in Physical Chemistry; Kemi med inriktning mot fysikalisk kemi;

   Sammanfattning : Proton-coupled electron transfer (PCET) from tyrosine (Y) and tryptophan (W) is vital to many redox reactions in Nature where PCET between several Ys, or Ws, or between a mix of Ys and Ws can be used to transfer electrons, or protons, or both over large distances of several Å. Studying the PCET reaction mechanisms of Y and W is important for fundamental knowledge, and can help researchers that wish to mimic redox reactions in Nature. LÄS MER

5. 4. Using de novo design proteins to explore tyrosine radicals and cation-π interactions

   Författare :Bruce W. Berry; Cecilia Tommos; Anders Hofer; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; tyrosine; radicals; cation-pi interactions; de novo designed proteins; biochemistry; biophysics; Biochemistry; biokemi;

   Sammanfattning : Redox cofactors and amino-acid free radicals play important roles in biology. Although many of the same cofactors and amino acids that form these radicals are found across a broad range of biological systems, identical cofactors can have different reduction potentials. The local environment plays a role in defining these redox potentials. LÄS MER

7. 5. Functional characterization of tyrosine and tryptophan transport in fibroblasts from healthy controls, patients with schizophrenia and bipolar disorder

   Författare :Ravi Vumma; Nikolaos Venizelos; Tommy Lewander; Dimitrios Kyriakidis; Örebro universitet; []
   Nyckelord :Fibroblasts; Tyrosine; Tryptophan; LAT1; Schizophrenia; Bipolar disorder; MEDICINE; MEDICIN; Biomedicin; Biomedicine;

   Sammanfattning : .... LÄS MER