Sökning: "TLR3"
Visar resultat 1 - 5 av 35 avhandlingar innehållade ordet TLR3.
1. Effects of the host defense peptide LL-37 on human cells : Immunomodulation and cytotoxicity
Sammanfattning : The human host defense peptide LL-37 has an essential role in the first line of defense against invading pathogens. This cathelicidin is mainly produced by immune cells and epithelial cells aligning the mucosal areas and is normally upregulated upon infection and inflammation. LÄS MER
2. Arthritogenecity of RNA and its degradation products
Sammanfattning : Viral infections often lead to arthralgias and overt arthritic states. Expression of double stranded RNA (dsRNA) is a common feature of all viruses during their replication and it has been suggested that it is able to induce production of pro-inflammatory cytokines, e.g., interferon-alpha (IFN-alpha). LÄS MER
3. Requirements for the Induction of Adaptive Immune Responses to Rotavirus
Sammanfattning : Rotavirus (RV) infections remain the leading cause of world-wide diarrhea-associated morbidity and mortality among children 200,000 deaths annually mostly in the low-income countries of Africa and Asia. Efficient clearance of the primary RV infection and protection from future re-infections is mediated by adaptive immune responses. LÄS MER
4. Toll-like Receptors in Allergic Rhinitis
Sammanfattning : Allergic rhinitis is an inflammatory disorder with the characteristic symptoms itching, sneezing, secretion and blockage upon allergen contact. In addition to the local inflammation in the nose, there is a systemic component that influences peripheral blood, bone marrow and lungs. LÄS MER
5. Emerging role of RIG-I-like receptors in antiviral innate immunity in airway structural cells
Sammanfattning : Respiratory viral infections, especially involving rhinovirus, are main triggers of exacerbations of asthma and COPD. These severe conditions are a great burden to both the individual and society and currently lack effective treatments. LÄS MER