Sökning: "TIMP- 3"
Visar resultat 21 - 25 av 26 avhandlingar innehållade orden TIMP- 3.
21. Immune regulation in multiple sclerosis : cytokines and metalloproteinases
Sammanfattning : Immunological mechanisms play a central role in the pathogenesis sclerosis (MS). In this study two groups of related immune variables are cytokines and metalloproteinases (MMPs), which regulate each other's production and activation. LÄS MER
22. Treatment of subacromial pain and rotator cuff tears
Sammanfattning : Shoulder pain is very common, affecting 14-21 % of the population at some time during their lifetime. The aims of this thesis were to improve the understanding of various aspects concerning the pathogenesis and treatment of subacromial pain and rotator cuff tears. LÄS MER
23. Matrix metalloproteinases in Helicobacter inducedgastritis
Sammanfattning : Helicobacter pylori infects the stomach and areas of gastric metaplasia in the duodenum. Theinfection leads to peptic ulcers or gastric cancers in 10-20% of infected individuals, while themajority are more or less asymptomatic. However, active chronic gastritis develops in all infectedindividuals, often in association with atrophic gastritis. LÄS MER
24. Circulating biomarkers in patients with abdominal aortic aneurysm
Sammanfattning : Abdominal aortic aneurysm (AAA) develops in 3-6% of the population over 65 years and affects mainly men. AAA has a complex etiology involving inflammation, proteolysis, fibrinolysis and coagulation. LÄS MER
25. Studies of molecular mechanisms of action of TNF antagonists in rheumatoid arthritis
Sammanfattning : Rheumatoid arthritis (RA) is a common chronic inflammatory disease characterized by progressive bone destruction that leads to joint deformity and physical disability. Even though several therapeutic drugs are available, none have emerged as an ideal RA treatment that delays joint destruction and halts disease progression. LÄS MER