Sökning: "TIMP- 3"

Visar resultat 16 - 20 av 26 avhandlingar innehållade orden TIMP- 3.

  1. 16. Matrix-degrading metalloproteinases and cytokines in multiple sclerosis and ischemic stroke

    Författare :Mathilde Cornelia Maria Kouwenhoven; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by blood-brain barrier breakdown, perivascular inflammation and demyelination. In ischemic stroke, an inflammatory reaction develops shortly after arterial occlusion. LÄS MER

  3. 17. Proteolytic imbalance in COPD : epidemiological and clinical aspects

    Författare :Robert Linder; Anders Blomberg; Anne Lindberg; Annelie F. Behndig; Arne Egesten; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Matrix metalloproteinases; MMP-9; MMP-12; lung function decline; epidemiology; COPD; OLIN; KOLIN; medicin; Medicine;

    Sammanfattning : Background: The complete pathologic mechanism behind the development of chronic obstructive pulmonary disease (COPD) remains unclear, but several risk factors have been identified, of which smoking is the most common. Proteolytic imbalance contributes to lung tissue degradation and is related to both smoking and COPD symptoms. LÄS MER

  4. 18. Tendinosis in Trigger Finger

    Författare :Anna-Carin Lundin; Per Aspenberg; Pernilla Eliasson T.; Johann Zdolsek; Göran Nylander; Lars Dahlin; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Trigger finger is one of the most common hand conditions, with a prevalence of almost 3%. The aetiology remains unclear even though many causes have been suggested. The prevailing paradigm is that the pathogenesis of trigger finger is ascribed to primary changes in the first fibrous condensation of the tendon sheath (A1-pulley). LÄS MER

  5. 19. Matrix degrading proteases in the ovary : expression and function

    Författare :Patrik Wahlberg; Tor Ny; Ilpo Huhtaniemi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; ovary; ovulation; corpus luteum; plasminogen; PA; MMP; rat; mouse; Biokemi; Biochemistry; Biokemi; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Extracellular matrix degrading proteases from the plasminogen (plg) activator (PA) and the matrix metalloproteinase (MMP) systems have been implicated as important mediators of ovulation and corpus luteum (CL) formation and regression. The aim of this thesis was to investigate the expression and regulation of PAs and MMPs in the ovary and to examine their functional roles for CL formation and function. LÄS MER

  7. 20. Dentine caries : acid tolerant microorganisms and aspects on collagen degradation

    Författare :Anders Hedenbjörk Lager; Malmö högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dental Caries; Collagen; Cariogenic Agents;

    Sammanfattning : Karies är en stor folksjukdom, trots att den både kan förebyggas och behandlas effektivt. Om man inte ingriper preventivt och låter det naturliga förloppet råda, kommer kariesangreppet till slut att bryta igenom emaljen och involvera även den underliggande dentinvävnaden. LÄS MER