Sökning: "TBARS"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet TBARS.

1. 1. Oxidative stress, antioxidative defence and outcome of gestation in experimental diabetic pregnancy

   Författare :Jonas Cederberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Diabetes; pregnancy; rat; ROS; free oxygen radicals; TBARS; isoprostanes; protein carbonyls; embryo; vitamin C; vitamin E; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

   Sammanfattning : Maternal type 1 diabetes is associated with an increased risk for foetal malformations. The mechanism by which diabetes is teratogenic is not fully known. Previous studies have demonstrated that radical oxygen species can contribute to the teratogenicity of glucose and diabetes. LÄS MER

3. 2. Antioxidant Activity of Bolivian Plant Secondary Metabolites

   Författare :Patricia Mollinedo; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytoprotection; Beta-carotene; TBARS; TEAC; ABTS; antioxidant activity; secondarymetabolites; Highland plains; plants; photoprotection; Organic chemistry; Organisk kemi;

   Sammanfattning : Certain climatologically-adverse conditions in the basin of the Poopo Lake, located on the high plateau of the Bolivian Altiplano, have prevented the existence of a reliable agricultural system and the impact on the population of the area has been severe. These problems have been the main motivation in choosing this region for this particular study. LÄS MER

4. 3. Oxidation of fish lipids during gastrointestinal in vitro digestion

   Författare :Karin Larsson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TBARS; HHE; salmon; lipids; TIM; fish; HNE; in vitro digestion; gastrointestinal; aldehydes; cod liver oil; n-3 PUFA; herring; lipid oxidation; MDA;

   Sammanfattning : Fish and many other marine organisms, contain long chain n-3 polyunsaturated fatty acids (LC n-3 PUFA), e.g. eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). EPA and DHA has shown beneficial effects in diseases related to inflammatory processes, such as cardiovascular diseases. LÄS MER

5. 4. Congenital malformations in experimental diabetic pregnancy : Aetiology and antioxidative treatment

   Författare :Martin Simán; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Diabetes; pregnancy; teratology; malformations; embryo; fetus; cataract; sorbitol; antioxidants; butylated hydroxytoluene; vitamin E; vitamin C; TBARS; neural crest cells; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

   Sammanfattning : Diabetes mellitus in pregnancy causes congenital malformations in the offspring.The aim of this work was to characterize biochemical and morphologic anomaliesin the conceptus of an animal model of diabetic pregnancy. In addition, apreventive treatment against diabetes-induced dysmorphogenesis was developed. LÄS MER

7. 5. Pathophysiology of 5-fluorouracil induced cardiotoxicity : a clinical and experimental study

   Författare :Magdalena Cwikiel; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; cell culture.; scanning and transmission electron microscopy; endothelium; lipid peroxidation; free radical; fibrinogen; 5-fluorouracil; blood and plasma viscosity; cardiotoxicity; cancerology; Cytologi; onkologi; cancer; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

   Sammanfattning : This thesis concerns the pathophysiology of 5-fluorouracil (5-FU) induced cardiotoxicity. The aim of the clinical studies was to determine whether hemorheological factors might explain 5-FU cardiotoxicity (I) and if the syndrome was associated with free radical (FR) generation and lipid peroxidation (II). LÄS MER