Sökning: "Stephen Toddo"

Hittade 1 avhandling innehållade orden Stephen Toddo.

1. 1. Engineering membrane proteins for production and topology

   Författare :Stephen Toddo; Daniel Daley; Roslyn Bill; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Membrane protein; Over-expression; Protein production; Codon optimization; Escherichia coli; AraH; NarK; mRNA secondary structure; coding sequence; ribosome binding site; RBS; topology; split-GFP; Biochemistry; biokemi;

   Sammanfattning : The genomes of diverse organisms are predicted to contain 20 – 30% membrane protein encoding genes and more than half of all therapeutics target membrane proteins. However, only 2% of crystal structures deposited in the protein data bank represent integral membrane proteins. LÄS MER