Sökning: "Stefan Bäckström"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Stefan Bäckström.

  1. 1. The hematopoietic transcription factor RUNX1 : a structural view

    Författare :Stefan Bäckström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; RUNX1; Runt domain; CBFβ; transcription factor; leukaemia; protein crystallography; anomalous diffraction; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; molekylärbiologi; Molecular Biology;

    Sammanfattning : The malfunction of the transcriptional regulator RUNX1 is the major cause of several variants of acute human leukemias and its normal function is to regulate the development of the blood system in concert with other transcriptional co-regulators. RUNX1 belongs to a conserved family of heterodimeric transcription factors that share a conserved DNA binding domain, the Runt domain (RD), named after the first member of this group – Runt - found in Drosophila melanogaster. LÄS MER

  3. 2. Apoptosis, proliferation, and sex steroid receptors in endometrium and endometrial carcinoma

    Författare :Marju Dahmoun; Torbjörn Bäckström; Karin Boman; Stefan Cajander; Seija Grénman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; estradiol; progesterone; steroid receptors; apoptosis; proliferation; endometrial carcinoma; Ki-67; p53; immunohistochemistry; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Sammanfattning : This thesis focuses on the involvement of apoptosis and proliferation in the mechanisms of menstruation and hormonal replacement therapy, HRT, as well as in the mechanisms of progesterone therapy in endometrial carcinoma. The aim of the first study was to investigate endometrium for 4 days before and for 2 days during menstruation. LÄS MER

  4. 3. Creating a Quality Management Culture : Focusing on Values and Leadership

    Författare :Pernilla Ingelsson; Håkan Wiklund; Ingela Bäckström; Stefan Lagrosen; Mittuniversitetet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Quality Management; Organizational culture; values; leadership; Lean; TQM; Kvalitetsledning; organisationskultur; värderingar; ledarskap; Lean; TQM;

    Sammanfattning : When applied successfully, the QM initiatives TQM and Lean enhance an organization´s ability to meet and exceed the expectations of the customers as well as co-workers and other stakeholders. There are however also QM initiatives that fail and one reason for this is the organization’s inability to create a supportive culture, a culture that rests on a number of values which aim at improving the quality and thereby customer satisfaction. LÄS MER

  5. 4. Distribution and chemical association of trace elements in incinerator residues and mining waste from a leaching perspective

    Författare :Naeem Saqib; Mattias Bäckström; Stefan Karlsson; William Mayes; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; trace elements; partitioning; fly ash; bottom ash; speciation; association; risk assessment; wood waste; incineration; mining waste; Chemistry; Kemi;

    Sammanfattning : Incineration is a mainstream strategy for solid waste management in Sweden and all over the world. Improved knowledge and understanding about the distribution of trace elements (in ashes) during incineration, and how trace element partitioning respond to the changes in waste composition, are important in terms of combustion process optimization and plant efficiency. LÄS MER

  7. 5. Utilization of waste materials for extraction of strategic metals : a biogeochemical approach

    Författare :Viktor Sjöberg; Stefan Karlsson; Bert Allard; Mattias Bäckström; Christian Ekberg; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biogeochemistry; ICP-QMS; MP AES; strategic metals; vanadium; uranium; mine waste; steel slag; shale residues; Enviromental Science; Miljövetenskap;

    Sammanfattning : Worldwide the modern society produces vast amounts of waste materials containing strategic and valuable metals. Some of them are of substantial economic or environmental significance if controlled recovery of metals can be performed or if uncontrolled release to the environment occurs. LÄS MER