Sökning: "Statin"

Visar resultat 1 - 5 av 66 avhandlingar innehållade ordet Statin.

  1. 1. The role of HMG-coenzyme A reductase (HMGCR) and statin medication in the Central Nervous System : Cognitive Functions, Metabolism, Feeding and Sleep Behaviour

    Författare :Ahmed Alsehli; Helgi B. Schiöth; Michael J. Williams; Heinrich Dircksen; Uppsala universitet; []
    Nyckelord :Statin; cardiovascular disease; HMGCR; PCSK9; sleep; insomnia; circadian; Chronotype; feeding;

    Sammanfattning : Millions of people are currently on statin medications (HMGCR inhibitors) to prevent cardiovascular diseases. Despite considerable central nervous system expression, little is known about HMGCR function in the brain. LÄS MER

  3. 2. Additives Increasing the Bone-Forming Potential around Calcium Phosphate Cements : Statin, Strontium and Silicon

    Författare :Maryam Montazerolghaem; Marjam Karlsson Ott; Håkan Engqvist; Pedro Granja; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Calcium Phosphate Cements; Osteoblast; Osteoclast; Monetite; Zebrafish; Simvastatin; Strontium; Silicon; Teknisk fysik med inriktning mot materialvetenskap; Engineering Science with specialization in Materials Science;

    Sammanfattning : More than one million people worldwide receive some kind of bone graft each year. Grafts are often needed following bone tumour removal or traumatic fractures to fill voids in the bone and to aid in the healing process. LÄS MER

  4. 3. Ischaemic heart disease - risk assessment, diagnosis, and secondary preventive treatment in primary care : with special reference to the relevance of exercise ECG

    Författare :Gunnar Nilsson; Eva Samuelsson; Thomas Mooe; Per Wändell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exercise ECG; Ischaemic heart disease; Myocardial infarction; Prehospital delay; Primary care; Prognosis; Referral; Statin; Secondary prevention; Arbets-EKG; hjärtinfarkt; ischemisk hjärtsjukdom; sekundärprevention; Family Medicine; allmänmedicin;

    Sammanfattning : Background: Ischaemic heart disease is a diagnostic and therapeutic challenge to most general practitioners. We sought to identify diagnostic characteristics and prognoses of patients in primary care that received exercise electrocardiography (ECG). We compared the ECG test results with respect to probability of subsequent cardiologist referrals. LÄS MER

  5. 4. Non-invasive ultrasound-based cardiovascular imaging in mouse models of atherosclerosis

    Författare :Julia Grönros; Göteborgs universitet; []
    Nyckelord :atherosclerosis; ultrasound-based imaging; cardiovascular disease; coronary artery; mouse; color Doppler echocardiography; ultrasound biomicroscopy; statin;

    Sammanfattning : Atherosclerosis is a chronic multi-factorial vascular disease. It generally requires large clinical settings and over many years to study the disease progression in man. Genetically modified mouse models of atherosclerosis have dramatically increased research feasibility within this area. LÄS MER

  7. 5. Circulating biomarkers in patients with abdominal aortic aneurysm

    Författare :Despina Flondell-Sité; Vaskulära sjukdomar - kliniska studier; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; matrix metalloproteinases; biomarkers; risk factors; fibrinolysis; coagulation; inflammation; Abdominal aortic aneurysm; statin; interleukin 6.; APC-PCI complex; serpine-1; endothelin-1;

    Sammanfattning : Abdominal aortic aneurysm (AAA) develops in 3-6% of the population over 65 years and affects mainly men. AAA has a complex etiology involving inflammation, proteolysis, fibrinolysis and coagulation. LÄS MER