Sökning: "Src"
Visar resultat 1 - 5 av 115 avhandlingar innehållade ordet Src.
1. C-SRC expression in neuroendocrine tumors : neuronal splice variants of C-SRC as diagnostic and prognostic markers in neuroblastoma
Sammanfattning : .... LÄS MER
2. Molecular mechanisms for activation of non-canonical TGFβ pathways and their importance during prostate cancer progression
Sammanfattning : Prostate cancer is the most common invasive cancer diagnosed in men and a major and growing health problem in Western countries. Deregulation of different pathways has been implicated in progression of prostate cancer, namely nuclear factor kappa enhancer binding protein (NF-κB), transforming growth factor β (TGFβ), phosphoinositide 3ʹ-kinase/AKT (PI3K/AKT) and Src kinase pathways. LÄS MER
3. Signal transduction in macrophages. Intracellular pathways activated by microbial constituents
Sammanfattning : Macrophages play an essential role in the defense against infection by phagocytosis and by production of inflammatory mediators. Such mediators are TNF? and eicosanoids. Many microbial agents elicit arachidonate release in macrophages that lead to the formation of eicosanoids. LÄS MER
4. The Role of Shb in Angiogenesis, FGF and VEGF Signalling in Endothelial Cells
Sammanfattning : Angiogenesis is defined as the formation of new capillary blood vessels from pre-existing ones. This process involves several steps including: migration, proliferation and differentiation of endothelial cells into blood vessels. LÄS MER
5. Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer
Sammanfattning : One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. LÄS MER