Sökning: "Skin Transplantation"

Visar resultat 1 - 5 av 52 avhandlingar innehållade orden Skin Transplantation.

  1. 1. Treatment of Skin Wounds with Cell Transplantation and Gene Transfer

    Författare :Tor Svensjö; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pigs; gene regulation; cell culture; fibroblasts; keratinocytes; wound healing; skin; gene transfer; Transplantation; gene therapy; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Background: A large number of different wound coverings have been used in order to improve the wound microenvironment, and thus accelerate repair. Since almost two centuries, clinicians and researchers have developed techniques for skin transplantation. LÄS MER

  3. 2. Costimulation Blockade in Experimental Transplantation

    Författare :Helene Malm; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; serologi; Immunologi; serology; Immunology; Medicin människa och djur ; Medicine human and vertebrates ; graft survival; anti-CD40L; CTLA4Ig; anti-LFA-1; costimulation blockade;

    Sammanfattning : Transplantation is the only cure for end-stage organ failure. With the transplantation follows the need for continuous treatment with immunosuppressive agents for as long as the graft functions, which entails major side effects. Less toxic treatments are therefore in great demand. Preferably, the treatment should also be limited in time. LÄS MER

  4. 3. Cancer in organ transplant recipients

    Författare :Caroline Stenman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; organ transplantation; skin cancer; heart transplantation; lung transplantation;

    Sammanfattning : Tens of thousands of transplantations are performed around the world each year. Organ transplant recipients (OTR) are obliged to receive life-long medical treatment with immunosuppressive drugs to ensure graft function. However, such medications entail an increased risk of developing a broad spectrum of malignancies, especially skin cancer. LÄS MER

  5. 4. Vitiligo and Piebaldism : Treatmant of Leucoderma by Transplantation of autologous melanocytes

    Författare :Mats J. Olsson; Hugh Zachariae; Uppsala universitet; []
    Nyckelord :Medical sciences; leucoderma; leukoderma; vitiligo; piebaldism; melanocytes; pigmentation; cell culturing; serum-free; transplantation; surgery; autoimmune disease; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatology and Venerology; dermatologi och venereologi;

    Sammanfattning : Background: Vitiligo and piebaldism are disorders in which the affected skin lack epidermal melanocytes. Vitiligo is acquired and can clinically be subgrouped, but the aetiology is still not fully understood. The most common type, generalized vitiligo (vitiligo vulgaris) has autoimmune involvement and affects about 1. LÄS MER

  7. 5. Induction of operational tolerance to allografts and xenografts

    Författare :Matthias Corbascio; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunologi; serologi; serology; Immunology; allograft; xenograft; heart transplantation; tolerance; anti-LFA-1; CTLA4Ig; anti-CD40L;

    Sammanfattning : Inhibition of the costimulatory molecules B7 and CD40L with CTLA4Ig and anti-CD40L administered only during the first week after transplantation induces indefinite survival of allo- and xenogeneic heart transplants and significantly prolongs skin grafts in C3H mice. However, this treatment protocol is not as effective in C57BL/6 mice which reject skin transplants with nearly the same median survival time as untreated controls. LÄS MER