Sökning: "Signalling"
Visar resultat 21 - 25 av 971 avhandlingar innehållade ordet Signalling.
21. Signalling pathways controlling bacterial adaptation
Sammanfattning : The conversion of environmental signals into cellular responses is a critically important process that occurs in all organisms. The ability to process information depends, in general, on complex signal transduction and regulatory networks that control genes required to cope with certain environmental conditions. LÄS MER
22. Functional analysis of Ipf1/Pdx1, MFng and Id during pancreatic growth and differentiation
Sammanfattning : The pancreas is an endodermally derived organ consisting of three major cell lineages. The endocrine cells, organised into the Islets of Langerhans, regulate blood glucose homeostasis by producing and secreting hormones such as glucagon and insulin into the bloodstream. LÄS MER
23. Evolution of cellular complexity and other remarkable features in Gemmataceae : Complex bacterial lineages defy prokaryotic trends
Sammanfattning : Bacteria of the family Gemmataceae belong the phylum Planctomycetes and are remarkable because of their complex cellular architectures, previously considered to be traits exclusive to eukaryotes. This thesis provides clues to the atypical cell envelope, the enhanced radiotolerance and the amazing cellular complexity of these bacteria. LÄS MER
24. On Fever Mechanisms & Preoptic Signalling
Sammanfattning : Fever, a 1-4 °C elevation of the body temperature, is part of the systemic inflammatory response to infection or tissue damage, and it is believed to be a potent host defence. The underlying physiological mechanisms of the febrile response are one of the two main objectives in this thesis, where studies conducted in whole animals (rats and mice), chiefly aimed at clarifying the cytokine cascade in fever. LÄS MER
25. Aspects of proteinase-activated receptor-2: A sensor of enzymatic activity at the cell surface
Sammanfattning : Information about extracellular proteolytic activity is transduced to the cell by a transmembrane G-protein coupled receptor subfamily. These receptors are activated by proteolytic cleavage in the extracellular amino-terminal domain and are thus termed proteinase-activated receptors (PARs). LÄS MER