Sökning: "Serotonin reuptake inhibition"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Serotonin reuptake inhibition.

  1. 1. On the hypersensitivity syndrome induced by the selective serotonin reuptake inhibiting antidepressant Zimeldine : A clinical and experimental study

    Detta är en avhandling från Linköping : Linköpings universitet

    Författare :Bengt-O Bengtsson; Linköpings universitet.; Linköpings universitet.; [1992]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Zimeldine; Norzimeldine; Hypersensitivity syndrome; Serotonin reuptake inhibition; Genetic disposition; Lymphocyte transformation test; Experimental allergic neuritis; Immunopharmacology; MEDICINE; MEDICIN;

    Sammanfattning : Zimeldine, the first selective neuronal serotonin (5-H1) reuptake inhibitor to be registered as an antidepressant was withdrawn from common use due to an acute flu-like adverse syndrome comprising fever, myalgia and/or arthralgia and signs of disturbed liver function. A few of these patients also developed a peripheral neuropathy, in the most serious form a Guillain-Barré syndrome (GBS). LÄS MER

  2. 2. On the possible role of serotonin and angiotensin for the respiratory abnormalities observed in panic disorder and premenstrual dysphoria

    Detta är en avhandling från Göteborg

    Författare :Marie Olsson; Göteborgs universitet.; Gothenburg University.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; panic disorder; premenstrual dysphoria; serotonin; paroxetine; PCPA; angiotensin; saralasin; respiration; respiratory variability; CO2; sodium lactate; female sex steroids; estrus cycle; Wistar rats;

    Sammanfattning : Panic disorder and premenstrual dysphoria are accompanied by intriguing abnormalities related to the control of respiration, including enhanced responsiveness to CO2 and enhanced respiratory variability. These aberrations do not seem to be shared by other psychiatric disorders, but appear to be relatively unique for panic disorder and premenstrual dysphoria. LÄS MER

  3. 3. 5-HT1A receptor ligands with putative antidepressant activity : Pharmacological studies in the rat

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Lotta Arborelius; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antidepressants; citalopram; dopamine; dorsal raphe nucleus; electrophysiology; frontal cortex; 5-HT; A receptors; microdialysis; serotonin; rat;

    Sammanfattning : Several studies suggest that serotonin(5-hydroxytryptamine, 5-HT)IA receptor agonists possess antidepressant activity. Probably these agents exert their therapeutic effect through stimulation of postsynaptic 5-HT,A receptors. LÄS MER

  4. 4. Noradrenergic augmentation strategies in the pharmacological treatment of depression and schizophrenia : An experimental study

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Physiology and Pharmacology

    Författare :Love Linnér; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The pharmacological treatment of depression and schizophrenia, two major psychiatric disorders, is largely based on modulation of central monoaminergic neurotransmission. However, currently available pharmacological treatment alternatives possess a relatively modest clinical efficacy, making them less than optimal. LÄS MER

  5. 5. Central nervous system targets for micturition control

    Detta är en avhandling från Department of Clinical Pharmacology, Lund University Hospital, S-221 85 Lund, Sweden

    Författare :Rikard Pehrson; Lunds universitet.; Lund University.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; central nervous system; Micturition; 5-HT; GABA; tramadol; NAD-299; CGP62349; apomorphine; cerebral infarction; toxikologi; farmaci; farmakognosi; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences;

    Sammanfattning : Popular Abstract in Swedish Urininkontinens utgör ett stort socialt problem, framför allt hos den äldre befolkningen. Kliniskt är urininkontinens iakttaget i större omfattning hos kvinnor än hos män, men studier antyder männen är mer drabbade än vad nuvarande statistik gör gällande. LÄS MER