Sökning: "Satellite cells"

Visar resultat 11 - 15 av 44 avhandlingar innehållade orden Satellite cells.

  1. 11. Peripheral nerve glia as multipotent progenitors in craniofacial development

    Författare :Maryam Khatibi Shahidi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Craniofacial development is complex. Numerous populations of progenitor cells coordinate activities to produce an array of highly integrated tissues inside the developing head. However, it is not clear how some key multipotent progenitors continue to exist in late developing head compartments. LÄS MER

  3. 12. Complex genomic rearrangements in rare brain disorders : genetic architecture and molecular consequences

    Författare :Jakob Schuy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Structural variants (SVs) within the genome, such as deletions, duplications, inversions, and translocations, are common but underappreciated causes of rare diseases. Complex genomic rearrangements involving two or more SVs in cis are incredibly challenging to detect. LÄS MER

  4. 13. Neuron-glial Interaction in the Developing Peripheral Nervous System

    Författare :Mikael Corell; Åsa Fex Svenningsen; Klas Kullander; Helgi Schöith; Heape Anthony; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Schwann cell; nonmyelinating Schwann cell; myelinating Schwann cell; development; proliferation; differentiation; myelin; neural stem cell; central nervous system; peripheral nervous system; enteric nervous system; N-cadherin; GABA; GAD; GABA B receptor; baclofen; CGP55485; Neuroscience; Neurovetenskap; Neuroscience; Neurovetenskap;

    Sammanfattning : The nervous system, including the brain, is the most sophisticated organ in the mammalian body. In such a complex network, neuron-glial interaction is essential and controls most developmental processes, such as stem cell fate determination, migration, differentiation, synapse formation, ensheathment and myelination. LÄS MER

  5. 14. Vascular Endothelial Growth Factor (VEGF) and Peripheral Nerve Regeneration

    Författare :Mariann Sondell; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Schwann cell; SCG; rat; peripheral nerve regeneration; neuropilin-1; nerve repair; mouse; growth factor; flk-1; axonal outgrowth; DRG; VEGF; Animal physiology; Djurfysiologi;

    Sammanfattning : This thesis concerns vascular endothelial growth factor (VEGF) and its possible role as a neurotrophic factor. I have investigated the effect of VEGF on neurons in culture but also in vivo, following a crush lesion of the sciatic nerve, and following nerve repair. LÄS MER

  7. 15. Distribution of CGRP and CGRP receptor in the trigeminovascular system and CNS

    Författare :Sajedeh Eftekhari; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CGRP; CLR; RAMP1; migraine; trigeminovascular system; pain; cerebellum;

    Sammanfattning : Calcitonin gene-related peptide (CGRP) has a key role in the pathophysiology of migraine and is associated with activation of the trigeminovascular system. Recently, CGRP receptor antagonists have been developed with clinical efficacy. LÄS MER