Sökning: "Saccharomyces castellii"

Hittade 5 avhandlingar innehållade orden Saccharomyces castellii.

  1. 1. Saccharomyces castellii: A new model organism for telomere research

    Författare :Eimantas Astromskas; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Naumovia castellii; Saccharomyces castellii; yeast; genetic tools; gene targeting; telomere; CDC13.; telomeric overhang;

    Sammanfattning : Telomeres are natural ends of eukaryotic chromosomes and perform a major role in cell biology. They protect chromosomes from degradation, fusions and the end replication problem. To study telomeres different model organisms are used including a number of yeast species. LÄS MER

  3. 2. Functional Studies of Telomere-Binding Proteins in Saccharomyces castellii

    Författare :Jenny Rhodin; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Rap1; DNA-binding domain; telomere evolution; Cdc13; telomerase; single-stranded overhang; telomere; yeast; Naumovia castellii; Saccharomyces castellii;

    Sammanfattning : Telomeres are the ends of linear eukaryotic chromosomes. The telomeres are essential for solving the end replication problem and they stabilize the genome by protection from degradation. The telomeres also protect the chromosomal ends from by being recognized as DNA breaks by the repair machinery, which could lead to end-to-end fusions. LÄS MER

  4. 3. Studies of molecular mechanisms of telomere maintenance in Naumovozyma castellii

    Författare :Ahu Karademir Andersson; Molekylär cellbiologi; []
    Nyckelord :YEAST; Saccharomyces castellii; Naumovozyma castellii; Processvity; Telomerase; Telomere; ALT; Strain engineering;

    Sammanfattning : Telomeres are special DNA-protein structures that protect ends of chromosomes from being recognized as double-strand breaks. Telomeres consist of tandemly repeated units of TG-rich DNA and associate with telomere-specific proteins. LÄS MER

  5. 4. RAP1 at the Yeast Telomere

    Författare :Johan Wahlin; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytogenetik; DNA-binding; Saccharomyces; yeast; telomeric repeat; telomere; RAP1; repressor activator protein 1; Genetics; cytogenetics; Genetik;

    Sammanfattning : Telomeres are specialized complexes of DNA and proteins that cap and confer stability to the ends of eukaryotic chromosomes. The telomeric DNA of most eukaryotes is composed of tandemly arranged short repeats. Within the budding yeasts these repeats are diverged in length as well as in nucleotide composition. LÄS MER

  7. 5. Genome dynamics and virulence in the human pathogen Candida glabrata

    Författare :Khadija Mohamed Ahmad; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pathogenic yeast; Candida glabrata; small chromosomes; Genome rearrangement; Haploid and diploid yeast; RNA interference.;

    Sammanfattning : Although the yeast Candida glabrata is considered to be a part of the commensal microflora in healthy individuals, during the last years it has been frequently isolated from patients with mucosal and systemic fungal infections. Now it is considered as the second most frequently isolated pathogenic yeast after Candida albicans. Despite its name, C. LÄS MER