Sökning: "SK-N-MC"

Hittade 5 avhandlingar innehållade ordet SK-N-MC.

  1. 1. Enterostatin - target proteins and intracellular mechanisms. Function in food intake and energy metabolism

    Författare :Karin Berger; Molekylär endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; energy metabolism; insulin; uncoupling protein; beta-casomorphin; opiate; SK-N-MC; INS-1; Medicin människa och djur ; Medicine human and vertebrates ; fat intake; F1F0-ATP synthase; appetite; enterostatin; satiety; obesity;

    Sammanfattning : Hunger and satiety are the results of complex neural events that involve several neurotransmitters and peptides. Enterostatin is an appetite-regulating peptide released in the intestine in response to fat ingestion. Enterostatin specifically decreases fat intake, but has also metabolic effects like inhibition of insulin secretion. LÄS MER

  3. 2. The cholecystokinin receptor family : molecular cloning and pharmacological characterization

    Författare :Isabelle Nilsson; Dan Larhammar; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cholecystokinin (CCK) and gastrin are hormones/neurotransmittors of the gastrointestinal tract and central nervous system. The receptors for gastrin and CCK are members of the G protein-coupled receptor family. The aim of this study was to clone and pharmacologically characterize vertebrate and invertebrate CCK receptors and splice variants. LÄS MER

  4. 3. Voltage-dependent anion channels (VDAC) in the plasma membrane induce apoptosis

    Författare :Nesar Akanda; Fredrik Elinder; Tuula Jalonen; Linköpings universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Physiology; Apoptosis; Cell membrane; Hippocampus; Membrane potentials; Neurons; Voltage-dependent anion channels; Medicine; Medicin;

    Sammanfattning : Apoptosis, or programmed cell death, is essential for proper development and functioning of the body systems. During development, apoptosis plays a central role to sculpt the embryo, and in adults, to maintain tissue homeostasis by eliminating redundant, damaged or effete cells. Therefore, a tight regulation of this process is essential. LÄS MER

  5. 4. Isolation and characterization of regulatory peptides and bioactive compounds

    Författare :Åke Norberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Isolation of peptides and other bioactive compounds is an important and often necessary step to get the total information about their structures. This is demonstrated by a number of different characterizations in this thesis. LÄS MER

  7. 5. Genes that modulate or mediate dopaminergic neurotransmission : expression of the human prodynorphin gene and association studies with candidate genes in an alcohol patient sample

    Författare :Thomas Geijer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :association study; alcoholism; DNA polymorphisms; dopamine receptors DRD2; DRD3; DRD4 ; tyrosine hydroxylase TH ; prodynorphin; messengerRNA; gene expression; promotor Stockholm 1997;

    Sammanfattning : The development of alcoholism may at least partly be attributed to the effect of ethanol on reward and reinforcement. As a genetic influence in the vulnerability to alcoholism and drug abuse has been documented, it is of interest to investigate genes active in brain structures which mediate reward and reinforcement. LÄS MER