Sökning: "SCFAs"
Visar resultat 1 - 5 av 23 avhandlingar innehållade ordet SCFAs.
1. Studies in beta cells and adipocytes in the context of obesity and T2D - focusing on PDE3B, OPN and SCFAs
Sammanfattning : Type 2 diabetes (T2D) is a heterogeneous disease characterized by altered lipid parameters and elevated glucose levels, as a direct consequence of impaired insulin signaling in target tissues and reduced insulin exocytosis from pancreatic β-cells. Obesity, which dramatically increases worldwide, is associated with insulin resistance and T2D. LÄS MER
2. Faecal short-chain fatty acids as an indicator of the status of intestinal microbial ecology
Sammanfattning : The aims of this study were to investigate how faecal concentrations of short chain fatty acids (SCFAs) reflect intestinal microbial ecology. Faecal SCFAs and water content were determined in 93 healthy volunteers to establish the normal values in man and the correlations between various SCFAs and between SCFAs and faecal water. LÄS MER
3. Gut microflora associated characteristics in children with celiac disease
Sammanfattning : Aim: The over-arching aim of this thesis was to study some metabolic functions of the gut microflora in children with known or screening detected celiac disease (CD) and their first-degree relatives. Materials: Study I. A number of 36 untreated CD children, 47 after at least 3 months on glutenfree diet (GFD) and 42 healthy controls (HC). Study II. LÄS MER
4. Role of Melatonin, Neuropeptide S and Short Chain Fatty Acids in Regulation of Duodenal Mucosal Barrier Function and Motility
Sammanfattning : The duodenal epithelium is regularly exposed to HCl, digestive enzymes, bacteria and toxins, and sometimes also to ethanol and drugs. The imbalance of aggressive factors in the intestinal lumen and mucosal barrier function increases the risk of tissue injury and inflammation. LÄS MER
5. Infant microbiota and short chain fatty acids - relation to lifestyle and effect on health
Sammanfattning : The commensal microbiota has both beneficial and negative effects on the host. It is a source of infectious and inflammatory microorganisms, but may also provide immune stimulation during a critical period during early infancy that possibly offers protection against allergy and other immune mediated diseases. LÄS MER