Sökning: "Retinal ganglion cells"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden Retinal ganglion cells.

  1. 1. Neurotrophic Factor Receptors in the Normal and Injured Visual System : Focus on Retinal Ganglion Cells

    Författare :Niclas Lindqvist; Finn Hallböök; Anders Kvanta; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; cell survival; gene expression; neurotrophic factor; receptor; retina; visual system; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; Medicinsk utvecklings- och neurobiologi;

    Sammanfattning : The focus of this thesis is the life and death of adult retinal ganglion cells (RGCs). RGCs are neurons that convey visual information from the retina to higher centers in the brain. LÄS MER

  2. 2. Modulation of the Progenitor Cell and Homeostatic Capacities of Müller Glia Cells in Retina : Focus on α2-Adrenergic and Endothelin Receptor Signaling Systems

    Författare :Mohammad Harun-Or-Rashid; Finn Hallböök; Per Ekström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha2-adrenergic receptor; Brimonidine; Brn3a; Dedifferentiation; Endothelin; EGFR; ERK1 2; Neuroprotection; NMDA; MIO-M1 human Müller cell; Müller cells; Retina; Retinal ganglion cells; Src-kinase; Transactivation.; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Müller cells are major glial cells in the retina and have a broad range of functions that are vital for the retinal neurons. During retinal injury gliotic response either leads to Müller cell dedifferentiation and formation of a retinal progenitor or to maintenance of mature Müller cell functions. LÄS MER

  3. 3. Generation of Retinal Neurons : Focus on the Proliferation and Differentiation of the Horizontal Cells and their Subtypes

    Författare :Henrik Boije; Finn Hallböök; Paul Layer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FoxN4; Ptf1a; PH3; G2-phase; Cell cycle arrest; Differentiation; Fate; Commitment; Neurogenesis; Follistatin; Neuroscience; Neurovetenskap; Neuroscience; Neurovetenskap;

    Sammanfattning : We have used the chicken retina as a model for investigating cell cycle regulation and cell fate commitment during central nervous system development. This thesis focuses on the characterization of and commitment to the horizontal cell fate in the retina. LÄS MER

  4. 4. Retinal ganglion cell examination with Optical Coherence Tomography reflects physiological and pathological changes in the eye and the brain

    Författare :Abbas Al-Hawasi; Neil Lagali; Yumin Link; Per Fagerholm; Per Söderberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Retinal ganglion cell; Retinal nerve fiber layer; Optical Coherence Tomography;

    Sammanfattning : The retinal ganglion cell is situated in the inner retina and its axons, composing the retinal nerve fiber layer (RNFL), leave the eye to form the optic nerve. These cells develop embryologically from the forebrain and later during development re-establish connections with different parts of the brain serving different purposes. LÄS MER

  5. 5. Neural limits of visual resolution

    Författare :Zoran Popovic; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell separation; cortical magnification; detection; estimated receptive field; high-pass filtered optotypes; nyquist limit; psychophysics; resolution; ganglion cells;

    Sammanfattning : Aims: The aim of this thesis was to formulate a model of retinal neural circuitry in humans based on morphological estimates of retinal cone and ganglion cell populations, to compare results based on this model to psychophysical measurements of visual resolution and identify the retinal neural factors that limit visual resolution.Materials & Methods: Total displacement of central ganglion cells from foveal cones was obtained by estimating the length of fibers of Henle in four human retinas along the nasal or vertical hemi-meridians. LÄS MER