Sökning: "ROC curves"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden ROC curves.

  1. 1. Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications

    Författare :Lars Ängquist; Matematisk statistik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; programming; actuarial mathematics; Statistik; cytogenetics; Genetik; cytogenetik; Mathematics; Matematik; Statistics; operations research; Genetics; ROC curves; conditioning loci; optimal score functions; noncentrality parameter; cost adjusted relative efficiency; exponential tilting; importance sampling; Monte Carlo simulation; normal approximation; crossover rate; process maximum; analytical approximation; significance calculations; NPL score; conditional linkage analysis; two-locus linkage analysis; Allele sharing; aktuariematematik; operationsanalys; programmering; gene-gene interaction; composite hypotheses; genetic disease models; classes of score functions; nonparametric linkage analysis;

    Sammanfattning : In linkage analysis or, in a wider sense, gene mapping one searches for disease loci along a genome. This is done by observing so called marker genotypes (alleles) and phenotypes (affecteds/unaffecteds) of a pedigree set, i.e. LÄS MER

  3. 2. Evaluation of image quality and diagnostic accuracy in breast tomosynthesis. Comparison with digital mammography and estimates of radiation risk

    Författare :Tony Svahn; Malmö Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diagnostic accuracy; breast tomosynthesis BT ; digital mammography DM ; average glandular dose AGD ; receiver operating characteristics ROC ; risk assessment; search-model SM ; proper ROC PROPROC ;

    Sammanfattning : Recent advances in the digital detector technology have paved the way for modalities such as two-dimensional digital mammography (DM) and three-dimensional breast tomosynthesis (BT). In this work, experimental studies were conducted to investigate the influence of reducing the average glandular dose (AGD) on detection of simulated lesions in DM and to compare the diagnostic accuracy of BT and DM. LÄS MER

  4. 3. Preprocessing perceptrons

    Författare :Lena Kallin Westin; Patrik Eklund; Lothar Gierl; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Datalogi; Preprocessing perceptron; Production line; Neural networks; Backpropagation; Fuzzy logic; ROC and QROC curves; Multivariate decision limits; Datalogi; Computer science; Datalogi; business data processing; administrativ databehandling;

    Sammanfattning : Reliable results are crucial when working with medical decision support systems. A decision support system should be reliable but also be interpretable, i.e. able to show how it has inferred its conclusions. LÄS MER

  5. 4. Personality disorder and violent criminality : a follow-up study with special reference to psychopathy and risk assessment

    Författare :Martin Grann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Forensic psychiatry; forensic psychology; personality disorders; psychopathy; PCL-R; HCR-20; VRAG; risk assessment; receiver operating characteristic analysis; neural network;

    Sammanfattning : Background: Structured models for the assessment of psychopathy and risk of violent recidivism have gained currency in forensic and correctional practice in many countries. The overall aim of this study was to test the predictive validity of some of these models among violent offenders with personality disorders in Sweden. LÄS MER

  7. 5. Diagnostic and Prognostic Value of Exercise Electrocardiographic Test Variables in Coronary Artery Disease

    Författare :Håkan Kronander; Lars-Åke Brodin; Erling Löfsjögård-Nilsson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; exercise ECG test; coronary artery disease; acute myocardial infarction; Medical engineering; Medicinsk teknik;

    Sammanfattning : The diagnostic performance of conventional analysis of the exercise electrocardiographic (ECG) test for the detection of coronary artery disease (CAD) is limited to 70-75%. The exercise ECG test is the most widely used non-invasive method for assessing CAD and even a small improvement in the diagnostic performance is important. LÄS MER