Sökning: "RBE"

Visar resultat 1 - 5 av 23 avhandlingar innehållade ordet RBE.

1. 1. Techniques for the increased utilization of dose response variability in proton therapy

   Författare :Erik Almhagen; Anders Ahnesjö; Alexandru Dasu; Nina Tilly; Oliver Jäkel; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RBE; Radiobiology; Proton Therapy; Dose Painting; Head and Neck Cancer; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Particle therapy is a form of radiation therapy in which protons and heavier ions are used, as opposed to photons in conventional radiation therapy. The biological effectiveness of particles compared to photons is often quantified as relative biological effectiveness (RBE). LÄS MER

3. 2. Averaged linear energy transfer and other beam quality descriptors inr elation to relative biological effectiveness

   Författare :Fredrik Kalholm; Niels Bassler; Iuliana Toma-Dasu; Emanuele Scifoni; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; LET; RBE; LQ-model; medicinsk strålningsfysik; Medical Radiation Physics;

   Sammanfattning : In radiotherapy with protons, a constant relative biological effectiveness (RBE) of 1.1 is traditionally applied, i.e. protons are assumed to be 10\% more effective than photons in killing cells. LÄS MER

4. 3. Biological effects of high energy radiation and ultra high dose rates

   Författare :Björn Zackrisson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiobiology; 50 MV x-rays; 50 MeV electrons; in vitro; in vivo; RBE; OER; ultra high dose-rate; radiobiological models; model selection; models of stochastic processes;

   Sammanfattning : Recently a powerful electron accelerator, 50 MeV race-track microtron, has been taken into clinical use. This gives the opportunity to treat patients with higher x-ray and electron energies than before. Furthermore, treatments can be performed were the entire fractional dose can be delivered in parts of a second. LÄS MER

5. 4. Protons, other Light Ions, and 60Co Photons : Study of Energy Deposit Clustering via Track Structure Simulations

   Författare :Gloria Bäckström; Anders Ahnesjö; Nina Tilly; José M. Fernández-Varea; Niels Bassler; Uppsala universitet; []
   Nyckelord :Proton; light ion; Co-60 photon; track structure Monte Carlo code; clustering patterns of energy deposit; RBE; Medicinsk radiofysik; Medical Radiophysics;

   Sammanfattning : Radiotherapy aims to sterilize cancer cells through ionization induced damages to their DNA whilst trying to reduce dose burdens to healthy tissues. This can be achieved to a certain extent by optimizing the choice of radiation to treat the patient, i.e. the types of particles and their energy based on their specific interaction patterns. LÄS MER

7. 5. Radiobiological investigations of proton and light ion therapy

   Författare :Nina Tilly; Michael Scholz; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiobiology; Monte Carlo method; Radiotherapy; high-energy instrumentation; Protons; Light ions; RBE; LET; Radiobiological models; Radiobiologi; medicinsk strålningsfysik; Medical Radiation Physics;

   Sammanfattning : During the last decade, the interest in proton and light ion beam therapy has increased considerably and several new centres are planned around the world. These particles have a large advantage due to their sharp physical dose distributions as compared to conventional radiotherapy beams. LÄS MER