Sökning: "Profilin-actin complex"

Hittade 5 avhandlingar innehållade orden Profilin-actin complex.

  1. 1. Profilin:actin in cell motility : A search for profilin:actin binding proteins

    Författare :Thomas Johansson; Roger Karlsson; Björn Öbrink; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; profilin; actin; Cell biology; Cellbiologi;

    Sammanfattning : The profilin:actin complex is a major source of actin for actin filament growth in vivo. A number of proteins regulating either profilin or actin has been described since profilin:actin was isolated during the 1970s. Since then, profilin and actin and their binding partners have been intensively studied. LÄS MER

  2. 2. Cross-linked Profilin:actin - A tool to study actin dynamics in non-muscle cells

    Författare :Staffan Grenklo; Roger Karlsson; Dan Lindholm; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; actin dynamics; profilin; actin; Profilin-actin complex; Cell motility; synaptic vesicle trafficing; Far western; fluorescence microscopy; Cell biology; Cellbiologi;

    Sammanfattning : The microfilament system, consisting of actin and a number of auxiliary proteins, is fundamental for cell motility. Its dynamic organization depends on receptor-mediated signals, leading to rapid polymerizations and depolymerizations of actin. LÄS MER

  3. 3. Cell Behavior and the Role of Profilin

    Författare :Yu Li; Roger Karlsson; Christophe Ampe; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Sammanfattning : Profilin is a key regulator of the microfilament system. It binds to actin monomers in a 1:1 complex, forming the profilin:actin complex, which is the major precursor of actin for filament formation in vivo. The distribution of profilin has been studied in a variety of cells. It is present not only in the cytoplasm but also in the nucleus. LÄS MER

  4. 4. The dynamic microfilament system : cellular organization of actin and profilin and their association with cell signalling

    Författare :Lucie Hájková; Karl-Eric Magnusson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Zoological Cell Biology; zoologisk cellbiologi;

    Sammanfattning : Active shape changes and movement of whole cells, and translocations within cells are essential to life. For instance, during embryogenesis cell migration is a central theme. Wound healing depends on increased and directed motile activity of several cell types. LÄS MER

  5. 5. Profilin in cell motility and signal transduction studies using site-specific mutagenesis

    Författare :Camilla Björkegren Sjögren; Tommy Andersson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Cellbiologi; Zoological Cell Biology; zoologisk cellbiologi;

    Sammanfattning : When a cell is stimulated by signalling molecules such as growth factors, one immediate response is an increased motile activity of the cell. Membrane lamella and spikes appear at the cell surface and perform undulating movements. LÄS MER