Sökning: "Presynaptic Inhibition"

Visar resultat 1 - 5 av 26 avhandlingar innehållade orden Presynaptic Inhibition.

  1. 1. Experimental studies of spinal mechanisms associated with muscle fatigue

    Författare :Ivana Kalezic; Vito Enrico Pettorossi; Umeå universitet; []
    Nyckelord :muscle fatigue; monosynaptic reflex; presynaptic inhibition; recurrent inhibition; fusimotor system; Fos-immunoreactivity; referral pain; kirurgi; Surgery;

    Sammanfattning : Muscle fatigue is ubiquitous in every day life.Muscle fatigue might be considered as an altered state of motor behaviour, which impairs motor performance. By contrast, muscle fatigue could also be considered a positive phenomenon, which protects muscle tissue from damage that might be incurred to it by overuse. LÄS MER

  3. 2. On spinal mechanisms for reflex control in man : modulation of Ia-afferent excitation with changes in muscle length, activation level and fatigue

    Författare :Maria M. Nordlund; Gymnastik- och idrottshögskolan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Electromyography; eccentric; concentric; presynaptic inhibition; H-reflex; central fatigue; twitch interpolation; muscle spindle; Medicin Teknik; Medicine Technology; Electromyography; eccentric; concentric; presynaptic inhibition; H-reflex; central fatigue; twitch interpolation; muscle spindle;

    Sammanfattning : To control muscle force, neural activation has to take alterations in muscle mechanics into account. This thesis assesses modulations in excitatory efficacy of Ia-afferents during muscle length changes at different levels of voluntary activation and during fatigue. LÄS MER

  4. 3. Regulation of experimentally induced airway obstruction

    Författare :Eva G. Lindström; Jan Lötvall; Linköpings universitet; []
    Nyckelord :airway obstruction; antigen; capsaicin; epithelium; inflammatory mediators; sensory neurons; tube preparation; tachykinins; formoterol; histamine; presynaptic inhibition; in vitro; guinea pig; MEDICINE; MEDICIN;

    Sammanfattning : Asthma is one of the commonest diseases in industrialized countries. The cause and mechanisms of !he disorder are still not fully unden;tood, al!hough it is known that inflammation in !he airways plays an important role. Inflammatory mediators, e.g. LÄS MER

  5. 4. Afferent input to midbrain dopamine neurones and its modulation : an electrophysiological study i vitro

    Författare :Pernilla Grillner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :dopamine neurones; synaptic transmission; NMDA receptors; L-type Ca2 channels; presynaptic inhibition; metabotropic glutamate receptors; muscarine; nicotine;

    Sammanfattning : Dopamine (DA) neurones of the ventral mesencephalon are involved in the control of reward related behaviour, cognitive functions and motor performances, and provide a critical site of action for major categories of neuropsychiatric drugs, such as antipsychotic agents, dependence producing drugs and anti-Parkinson medication. The midbrain DA neurones are mainly located in the substantia nigra pars compacta (SNPC) and the ventral tegmental area (VTA). LÄS MER

  7. 5. Neuromodulation via endocannabinoids and nitric oxide in the lamprey spinal cord

    Författare :Alexandros Kyriakatos; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The overall objective of this thesis is to increase our understanding of neural networks generating locomotion. These networks called Central Pattern Generators (CPG), are localized in the spinal cord and can generate the basic locomotor pattern in the absence of sensory or supraspinal inputs. LÄS MER