Sökning: "Polymer Gels"

Visar resultat 16 - 20 av 72 avhandlingar innehållade orden Polymer Gels.

1. 16. Thiol-Ene CHemistry and Dopa-Functional Materials towards Biomedical Applications

   Författare :Kristina Olofsson; Anders Hult; Michael Malkoch; Anders Daugaard; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Thiol-ene chemistry; DOPA; biomedical; UV; Fiber- och polymervetenskap; Fibre and Polymer Science;

   Sammanfattning : Thiol-ene chemistry is versatile and efficient and can be used as a powerful tool in polymer synthesis. In this thesis, the concept of thiol-ene chemistry has been central, where it has been explored as a tool for the synthesis of well-defined hydrogels and dopa-functional materials towards biomedical applications; such as hydrogels, primers for adhesive fixation of bone fractures, self-healing gels, and micelles for drug-delivery. LÄS MER

3. 17. Multi-functional Hyaluronan Based Biomaterials for Biomedical Applications

   Författare :Xia Yang; Dmitri Ossipov; Matthias Lutolf; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hyaluronan; biomaterials functionalizations; biomedical applications; orthogonal chemistry; drug delivery; tissue regeneration; MRI; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

   Sammanfattning : This thesis presents strategies for constructing multi-functional biomaterials based on hyaluronan (HA) derivatives for various biomedical applications, such as drug delivery, tissue regeneration, and imaging biomaterials. The aim of this study is to improve the functionalities of HA biomaterials as well as simplify the preparation procedures. LÄS MER

4. 18. Evaluation of Functionalized Biopolymers as a Step Toward Targeted Therapy of Osteoporosis

   Författare :Sujit Kootala; Jöns Hilborn; Peter Thomsen; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Osteoporosis; Bone regeneration; Biomaterials; Hyaluronic acid; Bisphosphonates; Osteoclasts; Osteoblasts; Growth factors; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry; Kemi med inriktning mot materialkemi; Chemistry with specialization in Materials Chemistry;

   Sammanfattning : The work presented in this thesis focuses on the development of strategies and smart bioactive materials for the treatment of osteoporosis. High and low molecular weight soluble hyaluronic acid-bisphosphonate (HA-BP) derivatives were investigated for their ability to inhibit osteoclasts. LÄS MER

5. 19. Radiotherapy Gel Dosimetry: Development and Application of Normoxic Polymer Gels

   Författare :Helen Gustafsson; Malmö Medicinsk strålningsfysik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical physics; radiology; tomography; medical instrumentation; Klinisk fysiologi; tomografi; medicinsk instrumentering; Radiofarmaceutisk teknik; Radiopharmaceutical technology; proton; LET; FT Raman spectroscopy; MRI; normoxic gel; IMRT; 3D verification; polymer gel dosimetry; radiologi;

   Sammanfattning : In many radiotherapy applications, true three-dimensional dosimetry with good spatial resolution that can be achieved in a single measurement would be of great value. Polymer gel dosimetry fulfils many of the demands on such a system. In this study, methods to facilitate the implementation of gel dosimetry have been investigated. LÄS MER

7. 20. Relating the Bulk and Interface Structure of Hyaluronan to Physical Properties of Future Biomaterials

   Författare :Ida Berts; Jöns Hilborn; Adrian R Rennie; Giovanna Fragneto; John W White; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hyaluronan; structure; bulk; interface; small-angle neutron scattering; neutron reflection; hydrogel; grafting; nanoparticles; protein interactions;

   Sammanfattning : This dissertation describes a structural investigation of hyaluronan (HA) with neutron scattering techniques. HA is a natural biopolymer and one of the major components of the extracellular matrix, synovial fluid, and vitreous humor. LÄS MER