Sökning: "Plasmin"

Visar resultat 11 - 15 av 35 avhandlingar innehållade ordet Plasmin.

  1. 11. Interactions of vitronectin and plasminogen with Helicobacter pylori

    Författare :Martina Pantzar; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteriology; Microbiology; catalase; extracellular matrix; adhesion; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Helicobacter pylori is the main cause of chronic gastritis and peptic ulcer disease in man and is also associated gastric cancer. The spiral shaped H. pylori moves through the gastric mucous layer and colonises the gastric epithelial cells. H. LÄS MER

  3. 12. Streptococcus pyogenes and its interactions with the human host

    Författare :Ulrika Ringdahl; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infections; mykologi; virologi; bakteriologi; M protein; Streptococcus pyogenes; plasminogen; fibrinogen; phagocytosis; platelet; Microbiology; bacteriology; virology; Mikrobiologi; mycology; Infektioner; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : We have found that a set of group A streptococcal strains, primarily associated with skin infections, express surface-associated M proteins that bind plasminogen and plasmin with high affinity. The binding is mediated by a common 13 amino acid internal repeated sequence located in the NH2-terminal surface-exposed portion of these M proteins. LÄS MER

  4. 13. Invasion promoting factors in endometriotic and endometrial tissue

    Författare :Christina Bruse; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Endometriosis; endometrium; PF; tPA; uPA; uPAR; PAI-1; PAI-2; IL-1beta; IL-6; TNFalpha.;

    Sammanfattning : Endometriosis is a common gynaecologic disorder, affecting women of fertile age with pelvic pain and infertility, and is characterized by the presence of endometrial glands and stroma outside the uterine cavity. Retrograde shed endometrial fragments are presumed to adhere to pelvic structures and grow invasively, thereby creating endometriotic tissue. LÄS MER

  5. 14. Bacterial interaction with the fibrinolytic system and extracellular matrix

    Författare :Thomas Herrman Eberhard; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :plasminogen; extracellular matrix; basement membrane; virulence factors; fibronectin; vitronectin; collagen; Haemophilus influenzae Neisseria meningitidis Streptococcus pneumoniae;

    Sammanfattning : Bacterial infection of host organisms is a state of complex interaction between the parasite and the host. Two critical steps in the infectious process are: Adhesion to the epithelial surfaces and penetration of tissue barriers to gain entrance to tissues and into the circulation. These two steps have been the subjects of this thesis. LÄS MER

  7. 15. The Plasminogen Activation System in Human Endometrium and Endometrial Cancer; Function, Tissue Localization and Prognostic Importance

    Författare :Johanna Nordengren; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; progesterone; estradiol; cultured cells; gene expression; prognosis; hyperplasia; neoplasm; endometrium; human; Plasminogen activators; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Sammanfattning : The release of urokinase plasminogen activator (uPA) from endometrial stromal cells decreased after progesterone stimulation, due to upregulation of PA inhibitor 1 (PAI-1) and uPA receptor (uPAR). Subsequently, the uPA:PAI-1 complex was internalized and degraded via uPAR. LÄS MER